{"refrec":{"BRefID":341492,"RR":"<b>Gordon, T.; Upadhyay, A.K.; Manni, L.; Huchon, D.; Shenkar, N.</b> (2021). And then there were three…: Extreme regeneration ability of the solitary chordate <i>Polycarpa mytiligera</i>. <i>Front. Cell Dev. Biol. 9</i>: 652466. <a href=\"https://dx.doi.org/10.3389/fcell.2021.652466\" target=\"_blank\">https://dx.doi.org/10.3389/fcell.2021.652466</a>","BEntID":338127,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Front. Cell Dev. Biol. 9</i>: 652466. <a href=\"https://dx.doi.org/10.3389/fcell.2021.652466\" target=\"_blank\">https://dx.doi.org/10.3389/fcell.2021.652466</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Gordon, T.; Upadhyay, A.K.; Manni, L.; Huchon, D.; Shenkar, N.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Gordon, T. <i>et al.</i>","Englishabstract":"Extensive regenerative ability is a common trait of animals capable of asexual development. The current study reveals the extraordinary regeneration abilities of the solitary ascidian <i>Polycarpa mytiligera</i>. Dissection of a single individual into separate fragments along two body axes resulted in the complete regeneration of each fragment into an independent, functional individual. The ability of a solitary ascidian, incapable of asexual development, to achieve bidirectional regeneration and fully regenerate all body structures and organs is described here for the first time. Amputation initiated cell proliferation in proximity to the amputation line. Phylogenetic analysis demonstrated the close affinity of <i>P. mytiligera</i> to colonial species. This evolutionary proximity suggests the ability for regeneration as an exaptation feature for colonial lifestyle. <i>P. mytiligera</i>’s exceptional regenerative abilities and phylogenetic position highlight its potential to serve as a new comparative system for studies seeking to uncover the evolution of regeneration and coloniality among the chordates.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"And then there were three…: Extreme regeneration ability of the solitary chordate <i>Polycarpa mytiligera</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-23 01:33:12.821491","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"tunicates, regenerative biology, cell proliferation,","OtherDescriptors":null,"Notes":null,"AnaPub":2021,"MonPub":null,"DateUpdate":"2022-10-04","DateCreate":"2021-08-09","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000645302400001","VABBcode":null,"OpenAcc":1,"DOI":"10.3389/fcell.2021.652466"},"refs":null,"anarec":{"AnaID":341492,"PubliDate":2021,"Pagination":"652466","XtraPublOfAnaID":null,"ISBN":null,"Volume":"9","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":341392,"SerRR":"Frontiers in Cell and Developmental Biology. Frontiers Media SA: Lausanne.  e-ISSN 2296-634X","StandardTitleSer":"Frontiers in Cell and Developmental Biology","ISSN":null,"AbbrevSer":"Front. Cell Dev. Biol.","StandardTitleMon":null,"StartPage":null,"Pages":null,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Gordon","Firstname":"Tal","Initials":"T.","Affiliation":"Tel Aviv Univ, George S Wise Fac Life Sci, Dept Zool, IL-69978 Tel Aviv, Israel.","Discriminator":null,"CorporateFlag":0,"BEntID":338127,"AutID":299956,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Upadhyay","Firstname":"Arnav Kumar","Initials":"A.K.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":338127,"AutID":462571,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Manni","Firstname":"Lucia","Initials":"L.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":338127,"AutID":356515,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Huchon","Firstname":"Dorothée","Initials":"D.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":338127,"AutID":462573,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Shenkar","Firstname":"Noa","Initials":"N.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":338127,"AutID":131551,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":338127,"BEntPrivate":null,"availability":[{"BInstID":364807,"LibID":36,"BRefID":341492,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"364807","RFID":null,"PaidValue":null,"Medium":"Server","Description":"VLIZ Open Access","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open access","URL":null,"ClassifID":53,"Classification":"Open access","ReqLink":null,"ClassifTypID":1,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":null,"InternalReq":0,"LoggedInReq":0,"Disclaimer":null,"DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":952,"SERpubls":[{"PublName":"Frontiers Media SA","City":"Lausanne"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"ASSEMBLEPlus Transnational Access","ThestID":181468,"Acronym":"KTPKO","ThesTermPath":"ASSEMBLEPlus Transnational Access"},{"ThesaurusTerm":"Phylogeny","ThestID":6184,"Acronym":"ASFA","ThesTermPath":"Biogeny > Phylogeny"},{"ThesaurusTerm":"Evolution","ThestID":2944,"Acronym":"ASFA","ThesTermPath":"Biological phenomena > Evolution"},{"ThesaurusTerm":"Scientific Publication","ThestID":169548,"Acronym":"KTPKO","ThesTermPath":"Scientific Publication"}],"thestermsASFA":[{"ThesaurusTerm":"ASSEMBLEPlus Transnational Access"},{"ThesaurusTerm":"Evolution"},{"ThesaurusTerm":"Phylogeny"},{"ThesaurusTerm":"Scientific Publication"}],"taxtermsASFA":[{"TaxTerm":"Polycarpa"},{"TaxTerm":"Polycarpa mytiligera"},{"TaxTerm":"Tunicata"}],"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":{"990":{"SpName":"Assemble","SpColID":990,"ParSpColID":null,"TopParID":null,"ShortName":"Assemble","URLLocation":null,"LibID":null,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"Assemble"},"952":{"SpName":"AssemblePlus","SpColID":952,"ParSpColID":990,"TopParID":990,"ShortName":"A+OR","URLLocation":"https://www.assembleplus.eu/assemble-plus-open-repository?module=ref&refid=","LibID":36,"OpenRepoFlag":1,"SpTypID":null,"TopParIDNotWebsite":990,"SpColPath":"Assemble/A+OR"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":338127,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":338127,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.3389/fcell.2021.652466","externalID":"10.3389/fcell.2021.652466","URLTypeCode":"DOI","URLID":96087,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":[{"ThesaurusTerm":"ASSEMBLEPlus Transnational Access","ThestID":181468,"Acronym":"KTPKO","ThesTypID":8,"ThesType":"Assemble KO Types"},{"ThesaurusTerm":"Evolution","ThestID":2944,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Phylogeny","ThestID":6184,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Scientific Publication","ThestID":169548,"Acronym":"KTPKO","ThesTypID":8,"ThesType":"Assemble KO Types"}],"taxterms":[{"TaxTerm":"Polycarpa","AphiaID":103538,"TaxtID":18124},{"TaxTerm":"Polycarpa mytiligera","AphiaID":215948,"TaxtID":23627},{"TaxTerm":"Tunicata [Sea squirts]","AphiaID":146420,"TaxtID":19392}],"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"ASSEMBLEPlus Transnational Access","DutchTerm":null,"ThestID":181468,"Acronym":"KTPKO","ThesTypID":8,"ThesType":"Assemble KO Types"},{"ThesaurusTerm":"Evolution","DutchTerm":"Evolutie","ThestID":2944,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Phylogeny","DutchTerm":"Fylogenie","ThestID":6184,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"},{"ThesaurusTerm":"Scientific Publication","DutchTerm":null,"ThestID":169548,"Acronym":"KTPKO","ThesTypID":8,"ThesType":"Assemble KO Types"}],"taxtermsFRIS":[{"TaxTerm":"Polycarpa","DutchTerm":null,"AphiaID":103538,"TaxtID":18124},{"TaxTerm":"Polycarpa mytiligera","DutchTerm":null,"AphiaID":215948,"TaxtID":23627},{"TaxTerm":"Tunicata","DutchTerm":"manteldieren","AphiaID":146420,"TaxtID":19392}],"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Chisala, Chilekwa, C.","newSesDate":{"date":"2021-08-09 09:11:54.130000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2022-10-04 11:42:22.407000","timezone_type":3,"timezone":"Europe/Brussels"}}}