{"refrec":{"BRefID":34998,"RR":"<b>Sakai, M.; Taniguchi, K.; Mamoto, K.; Ogawa, H.; Tabata, M.</b> (2001). Immunostimulant effects of nucleotide isolated from yeast RNA on carp, <i>Cyprinus carpio</i> L. <i>J. Fish Dis. 24</i>: 433-438. <a href=\"https://dx.doi.org/10.1046/j.1365-2761.2001.00314.x\" target=\"_blank\">https://dx.doi.org/10.1046/j.1365-2761.2001.00314.x</a>","BEntID":34998,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":" <i>J. Fish Dis. 24</i>: 433-438. <a href=\"https://dx.doi.org/10.1046/j.1365-2761.2001.00314.x\" target=\"_blank\">https://dx.doi.org/10.1046/j.1365-2761.2001.00314.x</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Sakai, M.; Taniguchi, K.; Mamoto, K.; Ogawa, H.; Tabata, M.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Sakai, M. <i>et al.</i>","Englishabstract":"Nucleotides from yeast RNA were evaluated for their ability to enhance the non-specific immune responses in carp, <i>Cyprinus carpio</i>. Oral administration of nucleotides to fish daily for 3 days resulted in enhanced responses of phagocytic and nitroblue tetrazolium (NBT) activities in kidney phagocytic cells. This activation of kidney cells was observed for at least 10 days post-treatment. The serum complement and lysozyme activities also increased in fish treated with nucleotides. Further more, the number of <i>Aeromonas hydrophila</i> in nucleotide-treated fish significantly decreased in the blood, kidney and liver after intraperitoneal injection. Thus yeast nucleotides appear to enhance non- specific immune responses in fish.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Immunostimulant effects of nucleotide isolated from yeast RNA on carp, <i>Cyprinus carpio</i> L.","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-14 01:31:06.327889","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2001,"MonPub":null,"DateUpdate":"2003-05-20","DateCreate":"2003-05-20","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000171586700001","VABBcode":null,"OpenAcc":0,"DOI":"10.1046/j.1365-2761.2001.00314.x"},"refs":null,"anarec":{"AnaID":34998,"PubliDate":2001,"Pagination":"433-438","XtraPublOfAnaID":null,"ISBN":null,"Volume":"24","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":44476,"SerRR":"Journal of Fish Diseases. Blackwell Science: Oxford; London; Edinburgh; Boston; Melbourne.  ISSN 0140-7775; e-ISSN 1365-2761","StandardTitleSer":"Journal of Fish Diseases","ISSN":"0140-7775","AbbrevSer":"J. 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