{"refrec":{"BRefID":35122,"RR":"<b>TenBrook, P.L.; Kendall, S.M.; Viant, M.R.; Tjeerdema, R.S.</b> (2003). Toxicokinetics and biotransformation of p-nitrophenol in red abalone (<i>Haliotis rufescens</i>). <i>Aquat. Toxicol. 62(4)</i>: 329-336. <a href=\"https://dx.doi.org/10.1016/S0166-445X(02)00103-0\" target=\"_blank\">https://dx.doi.org/10.1016/S0166-445X(02)00103-0</a>","BEntID":35122,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Aquat. Toxicol. 62(4)</i>: 329-336. <a href=\"https://dx.doi.org/10.1016/S0166-445X(02)00103-0\" target=\"_blank\">https://dx.doi.org/10.1016/S0166-445X(02)00103-0</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"TenBrook, P.L.; Kendall, S.M.; Viant, M.R.; Tjeerdema, R.S.","OrigTitleTranslFlag":0,"Authorstringtrunc":"TenBrook, P.L. <i>et al.</i>","Englishabstract":"Red abalone (<i>Haliotis rufescens</i>) were exposed to 3.6 µM (0.5 ppm) <sup>14</sup>C-labelled p-nitrophenol (PNP) for 24 h, then were allowed to depurate in clean seawater for another 24 h. Absorption, conditional uptake clearance and elimination rate constants were 0.12±0.04 h<sup>-1</sup>, 3.2±1.1 ml g<sup>-1</sup> h<sup>-1</sup> and 0.05±0.02 h<sup>-1</sup>, respectively. The sigmoidal shape of the PNP uptake curve suggests a biphasic process. A whole-organism total concentration factor (TCF) of 2.37±0.07 was determined from equilibrium tissue and water concentrations, with the highest concentration of PNP plus metabolites found in gill tissue (11.8±0.2 nmol g<sup>-1</sup>, wet weight). Digestive gland, foot muscle and remaining body tissues accumulated 8.8±0.9, 7.7±0.6 and 7.5±0.6 nmol g<sup>-1</sup> radiolabelled residues, respectively. Abalone depurated 91.6% of absorbed PNP within 24 h, of which 87.5±3.1% was unmetabolized parent compound, 13.1±3.1% was p-nitrophenylsulfate, 0.32±0.09% was p-nitroanisole, and 0.14±0.07% was p-acetamidophenol.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Toxicokinetics and biotransformation of p-nitrophenol in red abalone (<i>Haliotis rufescens</i>)","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-05-30 01:31:05.446950","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2003,"MonPub":null,"DateUpdate":"2019-08-09","DateCreate":"2003-05-26","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000181265200006","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/S0166-445X(02)00103-0"},"refs":null,"anarec":{"AnaID":35122,"PubliDate":2003,"Pagination":"329-336","XtraPublOfAnaID":null,"ISBN":null,"Volume":"62","Issue":"4","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42203,"SerRR":"Aquatic Toxicology. Elsevier Science: Tokyo; New York; London; Amsterdam.  ISSN 0166-445X; e-ISSN 1879-1514","StandardTitleSer":"Aquatic Toxicology","ISSN":"0166-445X","AbbrevSer":"Aquat. 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