{"refrec":{"BRefID":353110,"RR":"<b>Puspitasari, Y.E.; De Bruyne, T.; Foubert, K.; Aulanni'am, A.; Pieters, L.; Hermans, N.; Tuenter, E.</b> (2022). <i>Holothuria</i> triterpene glycosides: a comprehensive guide for their structure elucidation and critical appraisal of reported compounds. <i>Phytochemistry Reviews 21</i>: 1315-1358. <a href=\"https://dx.doi.org/10.1007/s11101-021-09783-z\" target=\"_blank\">https://dx.doi.org/10.1007/s11101-021-09783-z</a>","BEntID":350819,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Phytochemistry Reviews 21</i>: 1315-1358. <a href=\"https://dx.doi.org/10.1007/s11101-021-09783-z\" target=\"_blank\">https://dx.doi.org/10.1007/s11101-021-09783-z</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Puspitasari, Y.E.; De Bruyne, T.; Foubert, K.; Aulanni'am, A.; Pieters, L.; Hermans, N.; Tuenter, E.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Puspitasari, Y.E. <i>et al.</i>","Englishabstract":"Sea cucumbers or holothurians are marine invertebrates, belonging to the phylum Echinodermata (kingdom Animalia). In Asia, they are commonly used as food, while they are applied in traditional medicine as well. A wide range of secondary metabolites from these animals has been reported, but triterpene glycosides are the most predominant and most studied and are considered as valuable chemotaxonomic markers. With respect to this, the genus <i>Holothuria</i> is an important genus of sea cucumbers, given the high number and variety of triterpene glycosides previously reported. <i>Holothuria</i> triterpene glycosides are typically composed of a 3β-hydroxyholost-9(11)-ene aglycon and a glycosidic moiety comprised of one up to six sugar units, connected to position 3 of the sapogenin. In the past decade (2010–2020) as much as 63 saponins were identified for the first time in the <i>Holothuria</i> genus, of which 36 had not been reported before. Identification was mainly carried out by LC–MS (liquid chromatography—mass spectrometry) analysis, while also NMR (nuclear magnetic resonance) spectroscopy is often applied for structure elucidation. However, while carrying out a literature search on these compounds, various inconsistencies were observed. Therefore, this review intends to provide an overview of typical signals that can occur in NMR and MS data, accompanied with an extensive explanation of their interpretation, in order to facilitate any future research on identification/structure elucidation of <i>Holothuria</i> saponins. Moreover, the data published in the past decade were critically reviewed and various questionable results are discussed.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"<i>Holothuria</i> triterpene glycosides: a comprehensive guide for their structure elucidation and critical appraisal of reported compounds","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:01.897972","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Holothuria; Holothuriidae; Sea cucumber; Triterpene glycosides; Saponins","OtherDescriptors":null,"Notes":null,"AnaPub":2022,"MonPub":null,"DateUpdate":"2022-08-16","DateCreate":"2022-06-28","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000708808100003","VABBcode":null,"OpenAcc":0,"DOI":"10.1007/s11101-021-09783-z"},"refs":null,"anarec":{"AnaID":353110,"PubliDate":2022,"Pagination":"1315-1358","XtraPublOfAnaID":null,"ISBN":null,"Volume":"21","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":226468,"SerRR":"Phytochemistry Reviews. Springer: London; Dordrecht; Boston.  ISSN 1568-7767; e-ISSN 1572-980X","StandardTitleSer":"Phytochemistry Reviews","ISSN":"1568-7767","AbbrevSer":null,"StandardTitleMon":null,"StartPage":44,"Pages":1315,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":[{"YBRefID":354411,"RefStrFull":"<b>Puspitasari, Y.E.; De Bruyne, T.; Foubert, K.; Aulanni'am, A.; Pieters, L.; Hermans, N.; Tuenter, E.</b> (2022). Correction to: <i>Holothuria</i> triterpene glycosides: a comprehensive guide for their structure elucidation and critical appraisal of reported compounds. <i>Phytochemistry Reviews 21(4)</i>: 1359-1378. <a href=\"https://dx.doi.org/10.1007/s11101-022-09815-2\" target=\"_blank\">https://dx.doi.org/10.1007/s11101-022-09815-2</a>","RelID":4,"Relation":"Related to","StandardTitle":"Correction to: <i>Holothuria</i> triterpene glycosides: a comprehensive guide for their structure elucidation and critical appraisal of reported compounds"}],"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Puspitasari","Firstname":"Yunita","Initials":"Y.E.","Affiliation":"Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp","Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491913,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NatuRAPT","InsFSN":"Universiteit Antwerpen; Natural Products and Food Research and Analysis - Pharmaceutical Technology","ORCID":"0000-0002-1933-0435","PersID":38925,"InsID":14602},{"AutName":"De Bruyne","Firstname":"Tess","Initials":"T.","Affiliation":"Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp","Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491916,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NatuRAPT","InsFSN":"Universiteit Antwerpen; Natural Products and Food Research and Analysis - Pharmaceutical Technology","ORCID":"0000-0001-8597-2084","PersID":39380,"InsID":14602},{"AutName":"Foubert","Firstname":"Kenn","Initials":"K.","Affiliation":"Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp","Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491917,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NatuRAPT","InsFSN":"Universiteit Antwerpen; Natural Products and Food Research and Analysis - Pharmaceutical Technology","ORCID":null,"PersID":39378,"InsID":14602},{"AutName":"Aulanni'am","Firstname":"Aulanni","Initials":"A.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491064,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Pieters","Firstname":"Luc","Initials":"L.","Affiliation":"Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp","Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491920,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NatuRAPT","InsFSN":"Universiteit Antwerpen; Natural Products and Food Research and Analysis - Pharmaceutical Technology","ORCID":"0000-0002-8288-4254","PersID":39379,"InsID":14602},{"AutName":"Hermans","Firstname":"Nina","Initials":"N.","Affiliation":"Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp","Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491921,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NatuRAPT","InsFSN":"Universiteit Antwerpen; Natural Products and Food Research and Analysis - Pharmaceutical Technology","ORCID":"0000-0003-3946-7313","PersID":39381,"InsID":14602},{"AutName":"Tuenter","Firstname":"Emmy","Initials":"E.","Affiliation":"Natural Products and Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, University of Antwerp","Discriminator":null,"CorporateFlag":0,"BEntID":350819,"AutID":491922,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NatuRAPT","InsFSN":"Universiteit Antwerpen; Natural Products and Food Research and Analysis - Pharmaceutical Technology","ORCID":"0000-0003-3765-0341","PersID":39377,"InsID":14602}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":380223,"LibID":36,"BRefID":353110,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":null,"ShelfLocCode":"380223","RFID":null,"PaidValue":null,"Medium":"Server","Description":"Interne VLIZ documenten","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Non-open access","URL":null,"ClassifID":228,"Classification":"Non-open access","ReqLink":1,"ClassifTypID":3,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":1,"InternalReq":1,"LoggedInReq":1,"Disclaimer":"Disclaimer_VLIZ_Intern","DutchDisclaimer":"<p>Deze publicatie is enkel beschikbaar voor persoonlijk gebruik binnen de Innovocean site <br />en mag op geen enkele manier verder worden verspreid.</p>","FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Springer","City":"London; Dordrecht; Boston"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":[{"TaxTerm":"Holothuria"},{"TaxTerm":"Holothuriidae"}],"geotermsASFA":null,"collections":[{"Collection":"VLIZ Acknowledged Publications","ShortName":"VLIZ ackn"}],"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"},"941":{"SpName":"LifeWatch Species Information Backbone","SpColID":941,"ParSpColID":39,"TopParID":39,"ShortName":"LifeWatch Species Information Backbone","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":39,"SpColPath":"VLIZ ackn/LifeWatch Species Information Backbone"},"39":{"SpName":"VLIZ Acknowledged Publications","SpColID":39,"ParSpColID":null,"TopParID":null,"ShortName":"VLIZ ackn","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"VLIZ ackn"},"507":{"SpName":"World Register of Marine Species","SpColID":507,"ParSpColID":null,"TopParID":null,"ShortName":"WoRMS website","URLLocation":null,"LibID":null,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"WoRMS website"},"915":{"SpName":"World Register of Marine Species (WoRMS) acknowledged","SpColID":915,"ParSpColID":941,"TopParID":39,"ShortName":"WoRMS ackn","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":39,"SpColPath":"VLIZ ackn/LifeWatch Species Information Backbone/WoRMS ackn"},"947":{"SpName":"WoRMS ackn - direct reference","SpColID":947,"ParSpColID":915,"TopParID":39,"ShortName":"WoRMS ackn - direct","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":39,"SpColPath":"VLIZ ackn/LifeWatch Species Information Backbone/WoRMS ackn/WoRMS ackn - direct"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":350819,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":350819,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1007/s11101-021-09783-z","externalID":"10.1007/s11101-021-09783-z","URLTypeCode":"DOI","URLID":103770,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":null,"taxterms":[{"TaxTerm":"Holothuria","AphiaID":123456,"TaxtID":34635},{"TaxTerm":"Holothuriidae","AphiaID":731943,"TaxtID":16129}],"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":[{"TaxTerm":"Holothuria","DutchTerm":null,"AphiaID":123456,"TaxtID":34635},{"TaxTerm":"Holothuriidae","DutchTerm":null,"AphiaID":731943,"TaxtID":16129}],"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Bouchti, Zohra, Z.","newSesDate":{"date":"2022-06-28 12:58:37.713000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2022-08-16 07:20:25.083000","timezone_type":3,"timezone":"Europe/Brussels"}}}