{"refrec":{"BRefID":354017,"RR":"<b>Iha, C.; Dougan, K.E.; Varela, J.A.; Avila, V.; Jackson, C.J.; Bogaert, K.A.; Chen, Y.; Judd, L.M.; Wick, R.; Holt, K.E.; Pasella, M.M.; Ricci, F.; Repetti, S.I.; Medina, M.; Marcelino, V.R.; Chan, C.X.; Verbruggen, H.<\/b> (2021). Genomic adaptations to an endolithic lifestyle in the coral-associated alga <i>Ostreobium<\/i>. <i>Curr. Biol. 31(7)<\/i>: 1393-1402. <a href=\"https:\/\/dx.doi.org\/10.1016\/j.cub.2021.01.018\" target=\"_blank\">https:\/\/dx.doi.org\/10.1016\/j.cub.2021.01.018<\/a>","BEntID":351730,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Curr. Biol. 31(7)<\/i>: 1393-1402. <a href=\"https:\/\/dx.doi.org\/10.1016\/j.cub.2021.01.018\" target=\"_blank\">https:\/\/dx.doi.org\/10.1016\/j.cub.2021.01.018<\/a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Iha, C.; Dougan, K.E.; Varela, J.A.; Avila, V.; Jackson, C.J.; Bogaert, K.A.; Chen, Y.; Judd, L.M.; Wick, R.; Holt, K.E.; Pasella, M.M.; Ricci, F.; Repetti, S.I.; Medina, M.; Marcelino, V.R.; Chan, C.X.; Verbruggen, H.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Iha, C. <i>et al.<\/i>","Englishabstract":"The green alga <em>Ostreobium<\/em> is an important coral holobiont member, playing key roles in skeletal decalcification and providing photosynthate to bleached corals that have lost their dinoflagellate endosymbionts. <em>Ostreobium<\/em> lives in the coral\u2019s skeleton, a low-light environment with variable pH and O<sub>2<\/sub> availability. We present the <em>Ostreobium<\/em> nuclear genome and a metatranscriptomic analysis of healthy and bleached corals to improve our understanding of <em>Ostreobium<\/em>\u2019s adaptations to its extreme environment and its roles as a coral holobiont member. The <em>Ostreobium<\/em> genome has 10,663 predicted protein-coding genes and shows adaptations for life in low and variable light conditions and other stressors in the endolithic environment. This alga presents a rich repertoire of light-harvesting complex proteins but lacks many genes for photoprotection and photoreceptors. It also has a large arsenal of genes for oxidative stress response. An expansion of extracellular peptidases suggests that <em>Ostreobium<\/em> may supplement its energy needs by feeding on the organic skeletal matrix, and a diverse set of fermentation pathways allows it to live in the anoxic skeleton at night. <em>Ostreobium<\/em> depends on other holobiont members for vitamin B12, and our metatranscriptomes identify potential bacterial sources. Metatranscriptomes showed <em>Ostreobium<\/em> becoming a dominant agent of photosynthesis in bleached corals and provided evidence for variable responses among coral samples and different <em>Ostreobium<\/em> genotypes. Our work provides a comprehensive understanding of the adaptations of <em>Ostreobium<\/em> to its extreme environment and an important genomic resource to improve our comprehension of coral holobiont resilience, bleaching, and recovery.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Genomic adaptations to an endolithic lifestyle in the coral-associated alga <i>Ostreobium<\/i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-03 01:33:24.991285","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"coral holobiont; green algae; low-light adaptation; nuclear genome; Ostreobium","OtherDescriptors":null,"Notes":null,"AnaPub":2021,"MonPub":null,"DateUpdate":"2022-10-05","DateCreate":"2022-07-25","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000640082800004","VABBcode":null,"OpenAcc":0,"DOI":"10.1016\/j.cub.2021.01.018"},"refs":null,"anarec":{"AnaID":354017,"PubliDate":2021,"Pagination":"1393-1402","XtraPublOfAnaID":null,"ISBN":null,"Volume":"31","Issue":"7","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":72005,"SerRR":"Current Biology. 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