Document of bibliographic reference 354819

BibliographicReference record

Type

Bibliographic resource

Type of document

Journal article

BibLvlCode

AS

Title

Synthesis and characterization of nanohydroxyapatite (nHAp) from Meretrix meretrix clam shells and its in-vitro studies for biomedical applications

Abstract

Recycling of massive waste into valuable products promotes two in one advantages of waste recovery and a pollution-free environment. Preparation of Nanohydroxyapatite (nHAp) and its polymer composites using waste sea shells (natural precursor) are effectively useful in making artificial bone implants, bone cement, and toothpaste additives. The present work is focused to obtain nHAp with good crystalline nature and better biocompatibility using Meretrix Meretrix Clam shells as raw materials by the Co-precipitation method. To enhance the physio-chemical properties, polymers were used as capping agents. The functional group, particle size, thermal stability, phase transition, surface morphology, and electronic transition of atoms of the synthesized samples have been analyzed by spectrographic tools such as FT-IR, XRD, TG/DTA, FESEM/EDAX, XPS and HR-TEM with EDAX mapping respectively. Furthermore, the bacterial sensitivity of the sample against bacteria, the efficiency of the sample towards the formation of an apatite layer over the surface and its hemocompatibility nature were studied by antibacterial, SBF analysis and hemolysis assay respectively. This method of synthesis is free from hard chemicals and harmful by-products. Thus, the report of the present study suggests that it is promising to achieve nHAp with enhanced surface modification which indirectly promotes bone-bonding capability with natural living bone.

WebOfScience code

https://www.webofscience.com/wos/woscc/full-record/WOS:000840987700005

Bibliographic citation

Sindhya, A.; Johnson Jeyakumar, S.; Jothibas, M.; Pugalendhi, P. (2022). Synthesis and characterization of nanohydroxyapatite (nHAp) from Meretrix meretrix clam shells and its in-vitro studies for biomedical applications. Vacuum 204: 111341. https://dx.doi.org/10.1016/j.vacuum.2022.111341

Topic

Marine

Is peer reviewed

true