{"refrec":{"BRefID":356530,"RR":"<b>Pham, D.N.; Sokolov, E.P.; Falfushynska, H.; Sokolova, I.M.</b> (2022). Gone with sunscreens: responses of blue mussels (<i>Mytilus edulis</i>) to a wide concentration range of a UV filter ensulizole. <i>Chemosphere 309(Part 1)</i>: 136736. <a href=\"https://dx.doi.org/10.1016/j.chemosphere.2022.136736\" target=\"_blank\">https://dx.doi.org/10.1016/j.chemosphere.2022.136736</a>","BEntID":354245,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Chemosphere 309(Part 1)</i>: 136736. <a href=\"https://dx.doi.org/10.1016/j.chemosphere.2022.136736\" target=\"_blank\">https://dx.doi.org/10.1016/j.chemosphere.2022.136736</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Pham, D.N.; Sokolov, E.P.; Falfushynska, H.; Sokolova, I.M.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Pham, D.N. <i>et al.</i>","Englishabstract":"Organic UV filters have emerged as a new threat to marine organisms, but ecotoxicological studies have so far focused on only a few substances despite the chemical diversity of these synthetic sunscreen agents. Here we examined the responses of blue mussels <i>Mytilus edulis</i> to ensulizole, a non-lipophilic UV filter commonly found in the Baltic Sea. Mussels were exposed for three weeks to five ensulizole concentrations of 10, 10<sup>2</sup>, 10<sup>3</sup>, 10<sup>4</sup>, and 10<sup>5</sup> ng/L. Stress on stress response was evaluated by subjecting mussels to air exposure. A battery of biomarkers related to detoxification and antioxidant defense, oxidative stress damage, energy reserves and metabolism, autophagy, apoptosis, inflammation, and DNA damage was measured in the gills and the digestive gland. In general, ensulizole affected the antioxidant response, energy storage, and cell death-related processes in mussel tissues. Mussels exposed to low, environmentally relevant concentrations of ensulizole had a shorter air survival time than the control. Ensulizole often showed the non-monotonic concentration-response curves, suggesting the complex effects of this UV filter at molecular, biochemical, and organismal levels.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Gone with sunscreens: responses of blue mussels (<i>Mytilus edulis</i>) to a wide concentration range of a UV filter ensulizole","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"PBSA; SoS response; Oxidative stress; Bioenergetics; Cell signaling; Non-monotonic response","OtherDescriptors":null,"Notes":null,"AnaPub":2022,"MonPub":null,"DateUpdate":"2022-10-19","DateCreate":"2022-10-19","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000868476700004","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.chemosphere.2022.136736"},"refs":null,"anarec":{"AnaID":356530,"PubliDate":2022,"Pagination":"136736","XtraPublOfAnaID":null,"ISBN":null,"Volume":"309","Issue":"Part 1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42564,"SerRR":"Chemosphere. 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