Document of bibliographic reference 357933

BibliographicReference record

Type

Bibliographic resource

Type of document

Journal article

Type of document

Preprint

BibLvlCode

AS

Title

Ciguatera poisoning trace-back in Europe leads to a novel ciguatoxin-3C group characterization from the Indian Ocean

Abstract

The consumption of seafood containing marine biotoxins called ciguatoxins (CTXs) can result in ciguatera poisoning (CP), a globally prevalent seafood-born human illness. Since 2015 isolated and mass outbreaks of CP have occurred along the southwestern coast of India, however, no attributable CTXs have yet been identified. Herein, several CTXs are described in an often marketed snapper species (Lutjanus bohar) from southwest India. CTX3C-group compounds were identified by LC-MS/MS with a toxicity range of 0.79-5.39 ng CTX3C equivalent (eq.) g^-1 wet tissue eq., as determined by an in vitro cell (Neuro-2a) assay. Samples investigated were part of a 7,000 kg international shipment of frozen snapper product imported into the European Union and subsequently implicated in a 2020 CP outbreak in the Netherlands. The identification of CTX3C-group toxins in fish originating from coastal India suggests a re-evaluation of the current understanding of CTXs associated CP with seafood from the Indian Ocean region.

Bibliographic citation

Loeffler, C.; Spielmeyer, A.; Blashke, V.; Bodi, D.; Kappenstein, O. (2022). Ciguatera poisoning trace-back in Europe leads to a novel ciguatoxin-3C group characterization from the Indian Ocean. Research Square 1715170/v1: 1-20. https://dx.doi.org/10.21203/rs.3.rs-1715170/v1

Topic

Marine

Access rights

open access

Is accessible for free

true