{"refrec":{"BRefID":359815,"RR":"<b>Sengupta, A.; Dhar, J.; Danza, F.; Ghoshal, A.; Müller, S.; Kakavand, N.</b> (2022). Active reconfiguration of cytoplasmic lipid droplets governs migration of nutrient-limited phytoplankton. <i>Science Advances 8(44)</i>. <a href=\"https://dx.doi.org/10.1126/sciadv.abn6005\" target=\"_blank\">https://dx.doi.org/10.1126/sciadv.abn6005</a>","BEntID":357530,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Science Advances 8(44)</i>. <a href=\"https://dx.doi.org/10.1126/sciadv.abn6005\" target=\"_blank\">https://dx.doi.org/10.1126/sciadv.abn6005</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Sengupta, A.; Dhar, J.; Danza, F.; Ghoshal, A.; Müller, S.; Kakavand, N.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Sengupta, A. <i>et al.</i>","Englishabstract":"Nutrient availability, along with light and temperature, drives marine primary production. The ability to migrate vertically, a critical trait of motile phytoplankton, allows species to optimize nutrient uptake, storage, and growth. However, this traditional view discounts the possibility that migration in nutrient-limited waters may be actively modulated by the emergence of energy-storing organelles. Here, we report that bloom-forming raphidophytes harness energy-storing cytoplasmic lipid droplets (LDs) to biomechanically regulate vertical migration in nutrient-limited settings. LDs grow and translocate directionally within the cytoplasm, steering strain-specific shifts in the speed, trajectory, and stability of swimming cells. Nutrient reincorporation restores their swimming traits, mediated by an active reconfiguration of LD size and coordinates. A mathematical model of cell mechanics establishes the mechanistic coupling between intracellular changes and emergent migratory behavior. Amenable to the associated photophysiology, LD-governed behavioral shift highlights an exquisite microbial strategy toward niche expansion and resource optimization in nutrient-limited oceans.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Active reconfiguration of cytoplasmic lipid droplets governs migration of nutrient-limited phytoplankton","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:01.897972","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2022,"MonPub":null,"DateUpdate":"2022-12-22","DateCreate":"2022-12-22","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000918406800007","VABBcode":null,"OpenAcc":1,"DOI":"10.1126/sciadv.abn6005"},"refs":null,"anarec":{"AnaID":359815,"PubliDate":2022,"Pagination":null,"XtraPublOfAnaID":null,"ISBN":null,"Volume":"8","Issue":"44","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":248966,"SerRR":"Science Advances. 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