{"refrec":{"BRefID":361798,"RR":"<b>Jafari, H.; Alimoradi, H.; Delporte, C.; Bernaerts, K.V.; Heidari, R.; Podstawczyk, D.; Niknezhad, S.V.; Shavandi, A.</b> (2022). An injectable, self-healing, 3D printable, double network co-enzymatically crosslinked hydrogel using marine poly- and oligo-saccharides for wound healing application. <i>Applied Materials Today 29</i>: 101581. <a href=\"https://dx.doi.org/10.1016/j.apmt.2022.101581\" target=\"_blank\">https://dx.doi.org/10.1016/j.apmt.2022.101581</a>","BEntID":359514,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Applied Materials Today 29</i>: 101581. <a href=\"https://dx.doi.org/10.1016/j.apmt.2022.101581\" target=\"_blank\">https://dx.doi.org/10.1016/j.apmt.2022.101581</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Jafari, H.; Alimoradi, H.; Delporte, C.; Bernaerts, K.V.; Heidari, R.; Podstawczyk, D.; Niknezhad, S.V.; Shavandi, A.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Jafari, H. <i>et al.</i>","Englishabstract":"In this study, we designed dual network hydrogels with antioxidant and antibacterial activities using marine poly- and oligosaccharides with skin wound healing potential. The synergy between dual enzymatic co-crosslinking based on glucose oxidize (GOx)/horseradish peroxidase (HRP) and electrostatic interaction between positively charged chitooligosaccharides (COS) and phenolated chitosan with negatively charged phenolated alginate formed a hydrogel. The Gel-COS hydrogels exhibited toughness, self-healing, moldability, injectability, and 3D printability. Investigation of the physicochemical properties of the hydrogels exhibited a swelling ratio (&lt; 50%) and <em>in vitro</em> biodegradation after 9 days. Furthermore, the hydrogels exhibited antioxidant properties and antibacterial activity against <em>E. coli</em> and <em>S. aureus</em>. The hydrogels were not cytotoxic and enhanced the migration of 3D cell encapsulated 3T3-L1 fibroblasts, blood vessel formation, as well as <em>in vivo</em> wound healing in a rat model. The Gel-COS hydrogel can be considered a promising skin wound dressing material.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"An injectable, self-healing, 3D printable, double network co-enzymatically crosslinked hydrogel using marine poly- and oligo-saccharides for wound healing application","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:01.897972","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Marine polysaccharides; Injectable hydrogels; Glucose oxidize; Enzyme mediated crosslinking; Wound healing","OtherDescriptors":null,"Notes":null,"AnaPub":2022,"MonPub":null,"DateUpdate":"2023-03-06","DateCreate":"2023-03-06","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000837987700002","VABBcode":null,"OpenAcc":0,"DOI":"10.1016/j.apmt.2022.101581"},"refs":null,"anarec":{"AnaID":361798,"PubliDate":2022,"Pagination":"101581","XtraPublOfAnaID":null,"ISBN":null,"Volume":"29","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":263631,"SerRR":"Applied Materials Today. ELSEVIER SCIENCE BV: Amsterdam.  ISSN 2352-9407","StandardTitleSer":"Applied Materials Today","ISSN":"2352-9407","AbbrevSer":null,"StandardTitleMon":null,"StartPage":null,"Pages":null,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Jafari","Firstname":"Hafez","Initials":"H.","Affiliation":"Université libre de Bruxelles (ULB), École polytechnique de Bruxelles, 3BIO-BioMatter","Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":519068,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"BTL","InsFSN":"Université Libre de Bruxelles; Biomass Transformation Lab; Biomatter unit","ORCID":"0000-0003-4087-0273","PersID":39996,"InsID":14809},{"AutName":"Alimoradi","Firstname":"Houman","Initials":"H.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":448967,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Delporte","Firstname":"Christine","Initials":"C.","Affiliation":"Laboratory of Pathophysiological and Nutritional Biochemistry, Medical School, Université Libre de Bruxelles","Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":519070,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Bernaerts","Firstname":"Katrien","Initials":"K.V.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":464139,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Heidari","Firstname":"Reza","Initials":"R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":519072,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Podstawczyk","Firstname":"Daria","Initials":"D.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":490122,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Niknezhad","Firstname":"Seyyed","Initials":"S.V.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":519074,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Shavandi","Firstname":"Amin","Initials":"A.","Affiliation":"Université libre de Bruxelles (ULB), École polytechnique de Bruxelles, 3BIO-BioMatter","Discriminator":null,"CorporateFlag":0,"BEntID":359514,"AutID":519075,"OrderNr":8,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"BTL","InsFSN":"Université Libre de Bruxelles; Biomass Transformation Lab; Biomatter unit","ORCID":"0000-0002-0188-3090","PersID":40494,"InsID":14809}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":387335,"LibID":36,"BRefID":361798,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":null,"ShelfLocCode":"387335","RFID":null,"PaidValue":null,"Medium":"Server","Description":"Interne VLIZ documenten","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Non-open access","URL":null,"ClassifID":228,"Classification":"Non-open access","ReqLink":1,"ClassifTypID":3,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":1,"InternalReq":1,"LoggedInReq":1,"Disclaimer":"Disclaimer_VLIZ_Intern","DutchDisclaimer":"<p>Deze publicatie is enkel beschikbaar voor persoonlijk gebruik binnen de Innovocean site <br />en mag op geen enkele manier verder worden verspreid.</p>","FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"ELSEVIER SCIENCE BV","City":"Amsterdam"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":null,"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":359514,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":359514,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1016/j.apmt.2022.101581","externalID":"10.1016/j.apmt.2022.101581","URLTypeCode":"DOI","URLID":113643,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":null,"taxterms":null,"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":null,"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Bouchti, Zohra, Z.","newSesDate":{"date":"2023-03-06 14:30:51.887000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Bouchti, Zohra, Z.","updSesDate":{"date":"2023-03-06 14:30:51.887000","timezone_type":3,"timezone":"Europe/Brussels"}}}