{"refrec":{"BRefID":362146,"RR":"<b>Saelens, G.; Planckaert, S.; Martínez-Sernández, V.; Ubeira, F.M.; Devreese, B.; Gabriël, S.</b> (2022). Targeted proteomics and specific immunoassays reveal the presence of shared allergens between the zoonotic nematodes <i>Anisakis simplex</i> and <i>Pseudoterranova decipiens</i>. <i>NPG Scientific Reports 12(1)</i>: 4127. <a href=\"https://dx.doi.org/10.1038/s41598-022-08113-3\" target=\"_blank\">https://dx.doi.org/10.1038/s41598-022-08113-3</a>","BEntID":359862,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>NPG Scientific Reports 12(1)</i>: 4127. <a href=\"https://dx.doi.org/10.1038/s41598-022-08113-3\" target=\"_blank\">https://dx.doi.org/10.1038/s41598-022-08113-3</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Saelens, G.; Planckaert, S.; Martínez-Sernández, V.; Ubeira, F.M.; Devreese, B.; Gabriël, S.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Saelens, G. <i>et al.</i>","Englishabstract":"The family Anisakidae, mainly represented by <i>Anisakis simplex</i> s.l. and <i>Pseudoterranova decipiens</i>, encompasses zoonotic nematodes infecting many marine fish. Both are responsible for gastrointestinal disease in humans after ingestion of a live larva by consumption of undercooked fish, and, in the case of <i>A. simplex</i>, an allergic reaction may occur after consuming or even handling infected fish. Due to its phylogenetic relatedness with <i>A. simplex</i>, few studies investigated the allergenic potential of <i>P. decipiens</i>, yet none of them focused on its excretory/secretory (E/S) proteins that easily get missed when working solely on extracts from crushed nematodes. Moreover, these E/S allergens remain behind even when the larva has been removed during fish quality processing. Therefore, the aim was to investigate if <i>Anisakis-</i>like allergens could also be detected in both crushed and E/S <i>P. decipiens</i> protein extract using targeted mass spectrometry analysis and immunological methods. The results confirmed that at least five <i>A. simplex</i> allergens have homologous proteins in <i>P. decipiens;</i> a result that emphasizes the importance of also including E/S protein extracts in proteomic studies. Not only <i>A. simplex</i>, but also <i>P. decipiens</i> should therefore be considered a potential source of allergens that could lead to hypersensitivity reactions in humans.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Targeted proteomics and specific immunoassays reveal the presence of shared allergens between the zoonotic nematodes <i>Anisakis simplex</i> and <i>Pseudoterranova decipiens</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-18 01:32:33.132016","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2022,"MonPub":null,"DateUpdate":"2023-06-21","DateCreate":"2023-03-14","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000826474600172","VABBcode":null,"OpenAcc":1,"DOI":"10.1038/s41598-022-08113-3"},"refs":null,"anarec":{"AnaID":362146,"PubliDate":2022,"Pagination":"4127","XtraPublOfAnaID":null,"ISBN":null,"Volume":"12","Issue":"1","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":208093,"SerRR":"Scientific Reports (Nature Publishing Group). 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