{"refrec":{"BRefID":362805,"RR":"<b>Nikolaidis, M.; Mossialos, D.; Oliver, S.G.; Amoutzias, G.D.</b> (2020). Comparative analysis of the core proteomes among the <i>Pseudomonas</i> major evolutionary groups reveals species-specific adaptations for <i>Pseudomonas aeruginosa</i> and <i>Pseudomonas chlororaphis</i>. <i>Diversity 12(8)</i>: 289. <a href=\"https://dx.doi.org/10.3390/d12080289\" target=\"_blank\">https://dx.doi.org/10.3390/d12080289</a>","BEntID":360523,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Diversity 12(8)</i>: 289. <a href=\"https://dx.doi.org/10.3390/d12080289\" target=\"_blank\">https://dx.doi.org/10.3390/d12080289</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Nikolaidis, M.; Mossialos, D.; Oliver, S.G.; Amoutzias, G.D.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Nikolaidis, M. <i>et al.</i>","Englishabstract":"The <i>Pseudomonas</i> genus includes many species living in diverse environments and hosts. It is important to understand which are the major evolutionary groups and what are the genomic/proteomic components they have in common or are unique. Towards this goal, we analyzed 494 complete <i>Pseudomonas</i> proteomes and identified 297 core-orthologues. The subsequent phylogenomic analysis revealed two well-defined species (<i>Pseudomonas aeruginosa</i> and <i>Pseudomonas chlororaphis</i>) and four wider phylogenetic groups (<i>Pseudomonas fluorescens</i>, <i>Pseudomonas stutzeri</i>, <i>Pseudomonas syringae</i>, <i>Pseudomonas putida</i>) with a sufficient number of proteomes. As expected, the genus-level core proteome was highly enriched for proteins involved in metabolism, translation, and transcription. In addition, between 39–70% of the core proteins in each group had a significant presence in each of all the other groups. Group-specific core proteins were also identified, with <i>P. aeruginosa</i> having the highest number of these and <i>P. fluorescens</i> having none. We identified several <i>P. aeruginosa</i>-specific core proteins (such as <i>CntL</i>, <i>CntM</i>, <i>PlcB</i>, <i>Acp1</i>, <i>MucE</i>, <i>SrfA</i>, <i>Tse1</i>, <i>Tsi2</i>, <i>Tse3</i>, and <i>EsrC</i>) that are known to play an important role in its pathogenicity. Finally, a holin family bacteriocin and a mitomycin-like biosynthetic protein were found to be core-specific for <i>P. cholororaphis</i> and we hypothesize that these proteins may confer a competitive advantage against other root-colonizers.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Comparative analysis of the core proteomes among the <i>Pseudomonas</i> major evolutionary groups reveals species-specific adaptations for <i>Pseudomonas aeruginosa</i> and <i>Pseudomonas chlororaphis</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Pseudomonas; core-proteome; phylogenomics; comparative genomics; species-specific adaptations","OtherDescriptors":null,"Notes":null,"AnaPub":2020,"MonPub":null,"DateUpdate":"2023-03-28","DateCreate":"2023-03-27","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000577806900001","VABBcode":null,"OpenAcc":1,"DOI":"10.3390/d12080289"},"refs":null,"anarec":{"AnaID":362805,"PubliDate":2020,"Pagination":"289","XtraPublOfAnaID":null,"ISBN":null,"Volume":"12","Issue":"8","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":239468,"SerRR":"Diversity. 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