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The accessory nidamental glands of the cuttlefish, <i>Sepia officinalis</i> L. show an intensive orange-red coloration in mature females. This colour is due to carotenoid pigments which occur in symbiotic bacteria. 2. Six different pigmented strains of bacteria were isolated. 3. The main pigment in five of these strains is beta-carotene. 4. 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