{"refrec":{"BRefID":367006,"RR":"<b>van der Loos, L.M.; De Coninck, L.; Zell, R.; Lequime, S.; Willems, A.; De Clerck, O.; Matthijnssens, J.</b> (2023). Highly divergent CRESS DNA and picorna-like viruses associated with bleached thalli of the green seaweed <i>Ulva</i>. <i>Microbiology Spectrum 11(5)</i>: 1-25. <a href=\"https://dx.doi.org/10.1128/spectrum.00255-23\" target=\"_blank\">https://dx.doi.org/10.1128/spectrum.00255-23</a>","BEntID":364730,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Microbiology Spectrum 11(5)</i>: 1-25. <a href=\"https://dx.doi.org/10.1128/spectrum.00255-23\" target=\"_blank\">https://dx.doi.org/10.1128/spectrum.00255-23</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"van der Loos, L.M.; De Coninck, L.; Zell, R.; Lequime, S.; Willems, A.; De Clerck, O.; Matthijnssens, J.","OrigTitleTranslFlag":0,"Authorstringtrunc":"van der Loos, L.M. <i>et al.</i>","Englishabstract":"Marine macroalgae (seaweeds) are important primary producers and foundation species in coastal ecosystems around the world. Seaweeds currently contribute to an estimated 51% of the global mariculture production, with a long-term growth rate of 6% per year, and an estimated market value of more than US$11.3 billion. Viral infections could have a substantial impact on the ecology and aquaculture of seaweeds, but surprisingly little is known about virus diversity in macroalgal hosts. Using metagenomic sequencing, we characterized viral communities associated with healthy and bleached specimens of the commercially important green seaweed <i>Ulva</i>. We identified 20 putative new and divergent viruses, of which the majority belonged to the Circular Rep-Encoding Single-Stranded (CRESS) DNA viruses [single-stranded (ss)DNA genomes], <i>Durnavirales</i> [double-stranded (ds)RNA], and <i>Picornavirales</i> (ssRNA). Other newly identified RNA viruses were related to the <i>Ghabrivirales</i>, the <i>Mitoviridae</i>, and the <i>Tombusviridae</i>. Bleached <i>Ulva</i> samples contained particularly high viral read numbers. While reads matching assembled CRESS DNA viruses and picorna-like viruses were nearly absent from the healthy <i>Ulva</i> samples (confirmed by qPCR), they were very abundant in the bleached specimens. Therefore, bleaching in <i>Ulva</i> could be caused by one or a combination of the identified viruses but may also be the result of another causative agent or abiotic stress, with the viruses simply proliferating in already unhealthy seaweed tissue. This study highlights how little we know about the diversity and ecology of seaweed viruses, especially in relation to the health and diseases of the algal host, and emphasizes the need to better characterize the algal virosphere.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Highly divergent CRESS DNA and picorna-like viruses associated with bleached thalli of the green seaweed <i>Ulva</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2025-09-25 01:36:50.712317","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"RNA viruses, DNA viruses","OtherDescriptors":null,"Notes":null,"AnaPub":2023,"MonPub":null,"DateUpdate":"2025-09-18","DateCreate":"2023-09-18","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:001107303900012","VABBcode":null,"OpenAcc":1,"DOI":"10.1128/spectrum.00255-23"},"refs":null,"anarec":{"AnaID":367006,"PubliDate":2023,"Pagination":"1-25","XtraPublOfAnaID":null,"ISBN":null,"Volume":"11","Issue":"5","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":292075,"SerRR":"Microbiology Spectrum. ASM Press: Washington.  ISSN 2165-0497; e-ISSN 2165-0497","StandardTitleSer":"Microbiology Spectrum","ISSN":"2165-0497","AbbrevSer":null,"StandardTitleMon":null,"StartPage":1,"Pages":25,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"van der Loos","Firstname":"Luna","Initials":"L.M.","Affiliation":"Phycology Research Group, Department of Biology, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":467284,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Biologie; Onderzoeksgroep Fycologie","ORCID":"0000-0003-3686-2844","PersID":38604,"InsID":651},{"AutName":"De Coninck","Firstname":"Lander","Initials":"L.","Affiliation":"Laboratory of Clinical and Epidemiological Virology, Laboratory of Viral Metagenomics, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven","Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":539145,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Katholieke Universiteit Leuven; Departement Microbiologie en Immunologie; Afdeling Klinische en epidemiologische virologie","ORCID":null,"PersID":45275,"InsID":291},{"AutName":"Zell","Firstname":"Roland","Initials":"R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":539146,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Lequime","Firstname":"Sebastian","Initials":"S.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":539147,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Willems","Firstname":"Anne","Initials":"A.","Affiliation":"Laboratory of Microbiology, Department Biochemistry and Microbiology, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":539148,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Biochemie en Microbiologie; Laboratorium voor Microbiologie","ORCID":"0000-0002-8421-2881","PersID":10817,"InsID":1605},{"AutName":"De Clerck","Firstname":"Olivier","Initials":"O.","Affiliation":"Phycology Research Group, Department of Biology, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":133532,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"Universiteit Gent; Faculteit Wetenschappen; Vakgroep Biologie; Onderzoeksgroep Fycologie","ORCID":"0000-0002-3699-8402","PersID":2518,"InsID":651},{"AutName":"Matthijnssens","Firstname":"Jelle","Initials":"J.","Affiliation":"Laboratory of Clinical and Epidemiological Virology, Laboratory of Viral Metagenomics, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven","Discriminator":null,"CorporateFlag":0,"BEntID":364730,"AutID":539150,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":"KU Leuven; Rega-instituut; Department of Microbiology and Immunology","ORCID":"0000-0003-1188-9733","PersID":38654,"InsID":13569}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":393498,"LibID":36,"BRefID":367006,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"393498","RFID":null,"PaidValue":null,"Medium":"Server","Description":"VLIZ Open Access","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open access","URL":null,"ClassifID":53,"Classification":"Open access","ReqLink":null,"ClassifTypID":1,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":null,"InternalReq":0,"LoggedInReq":0,"Disclaimer":null,"DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"ASM Press","City":"Washington"}],"MONpubls":null,"pictures":[],"thestermsPath":[{"ThesaurusTerm":"Seaweed","ThestID":9676,"Acronym":"ASFA","ThesTermPath":"Seaweed"}],"thestermsASFA":null,"taxtermsASFA":[{"TaxTerm":"Chlorophyta"},{"TaxTerm":"Ulva"}],"geotermsASFA":null,"collections":[{"Collection":"OMA - Open Marien Archief","ShortName":"OMA"},{"Collection":"VLIZ Acknowledged Publications","ShortName":"VLIZ ackn"}],"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"},"1014":{"SpName":"Brilliant Marine Research Idea grant","SpColID":1014,"ParSpColID":39,"TopParID":39,"ShortName":"BMRI","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":39,"SpColPath":"VLIZ ackn/BMRI"},"991":{"SpName":"EMBRC acknowledged","SpColID":991,"ParSpColID":null,"TopParID":null,"ShortName":"EMBRC ackn","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"EMBRC ackn"},"1019":{"SpName":"EMBRC Acknowledged A1","SpColID":1019,"ParSpColID":991,"TopParID":991,"ShortName":"EMBRC Ackn A1","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":991,"SpColPath":"EMBRC ackn/EMBRC Ackn A1"},"221":{"SpName":"OMA - Open Marien Archief","SpColID":221,"ParSpColID":null,"TopParID":null,"ShortName":"OMA","URLLocation":null,"LibID":36,"OpenRepoFlag":1,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"OMA"},"39":{"SpName":"VLIZ Acknowledged Publications","SpColID":39,"ParSpColID":null,"TopParID":null,"ShortName":"VLIZ ackn","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"VLIZ ackn"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":364730,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":364730,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1128/spectrum.00255-23","externalID":"10.1128/spectrum.00255-23","URLTypeCode":"DOI","URLID":119026,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":[{"ThesaurusTerm":"Seaweed","ThestID":9676,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxterms":[{"TaxTerm":"Chlorophyta [green algae]","AphiaID":801,"TaxtID":15129},{"TaxTerm":"Ulva [Green laver]","AphiaID":144296,"TaxtID":25155}],"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":[{"ThesaurusTerm":"Seaweed","DutchTerm":"Zeewieren","ThestID":9676,"Acronym":"ASFA","ThesTypID":1,"ThesType":"ASFA Thesaurus List"}],"taxtermsFRIS":[{"TaxTerm":"Chlorophyta","DutchTerm":"Groenwieren","AphiaID":801,"TaxtID":15129},{"TaxTerm":"Ulva","DutchTerm":null,"AphiaID":144296,"TaxtID":25155}],"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Chisala, Chilekwa, C.","newSesDate":{"date":"2023-09-18 14:35:09.323000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Lyssens, Liesbeth, L.","updSesDate":{"date":"2025-09-18 16:35:09.130000","timezone_type":3,"timezone":"Europe/Brussels"}}}