Document of bibliographic reference 367185
BibliographicReference record
- Type
- Bibliographic resource
- Type of document
- Journal article
- BibLvlCode
- AS
- Title
- Cembrane diterpenoids: chemistry and pharmacological activities
- Abstract
- Cembrane diterpenoids (cembranoids), characterized by a 14-membered carbon ring and wide variety of functional groups, found in marine and terrestrial organisms. Many studies have shown that cembrane diterpenoids have cytotoxic and anti-inflammatory activities and are widely used in the development of new drugs. This review covered publications from 2011 to 2022 and classified the cembrane-type diterpenoids into isopropyl (ene) type, γ-lactone or unsaturated five-membered ring, δ-lactone or unsaturated six-membered ring, ε-lactone or unsaturated seven-membered ring, and other cembrane diterpenes. In addition, the biological activity and structure-activity relationship were summarized. This will provide guidance for new cembrane-type diterpenes as lead compounds to explore their potential application for treating cancer and inflammatory diseases.
- WebOfScience code
- https://www.webofscience.com/wos/woscc/full-record/WOS:001001515600001
- Bibliographic citation
- Zhang, N.; Xu, W.; Yan, Y.; Chen, M.; Li, H.; Chen, L. (2023). Cembrane diterpenoids: chemistry and pharmacological activities. Phytochemistry 212: 113703. https://dx.doi.org/10.1016/j.phytochem.2023.113703
- Topic
- Marine
- Terrestrial
- Is peer reviewed
- true
Authors
- author
-
- Name
- Na Zhang
- author
-
- Name
- Wei Xu
- author
-
- Name
- Yushu Yan
- author
-
- Name
- Mengjie Chen
- author
-
- Name
- Hua Li
- author
-
- Name
- Lixia Chen