{"refrec":{"BRefID":367660,"RR":"<b>Palaniyappan, S.; Sridhar, A.; Kari, Z.A.; Téllez-Isaías, G.; Ramasamy, T.</b> (2023). Evaluation of phytochemical screening, pigment content, in vitro antioxidant, antibacterial potential and GC-MS metabolite profiling of green seaweed <i>Caulerpa racemosa</i>. <i>Mar. Drugs 21(5)</i>: 278. <a href=\"https://dx.doi.org/10.3390/md21050278\" target=\"_blank\">https://dx.doi.org/10.3390/md21050278</a>","BEntID":365385,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Mar. Drugs 21(5)</i>: 278. <a href=\"https://dx.doi.org/10.3390/md21050278\" target=\"_blank\">https://dx.doi.org/10.3390/md21050278</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Palaniyappan, S.; Sridhar, A.; Kari, Z.A.; Téllez-Isaías, G.; Ramasamy, T.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Palaniyappan, S. <i>et al.</i>","Englishabstract":"Exploration of seaweeds to unravel their bioactive metabolites from the perspective of wider applications gained substantial importance. The present study was performed to investigate the total phenolic, flavonoid, tannin content, antioxidant activity and antibacterial potential of various solvent extracts of green seaweed <i>Caulerpa racemosa</i>. The methanolic extract showed higher phenolic (11.99 ± 0.48 mg gallic acid equivalents/g), tannin (18.59 ± 0.54 mg tannic acid equivalents/g) and flavonoid (33.17 ± 0.76 mg quercetin equivalents/g) content than other extracts. Antioxidant activity was determined by using 2,2-diphenylpicrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assay with different concentrations of <i>C. racemosa</i> extracts. The methanolic extract showed higher scavenging potential in both the DPPH and ABTS activity with the inhibition value of 54.21 ± 1.39% and 76.62 ± 1.08%, respectively. Bioactive profiling was also identified by using Gas chromatography-mass spectrometry (GC-MS) and Fourier transform infrared (FT-IR) techniques. These studies revealed the presence of valuable bioactive compounds in <i>C. racemosa</i> extracts and these compounds might be responsible for antimicrobial, antioxidant, anticancer and anti-mutagenic properties. Major compounds identified in GC-MS were 3,7,11,15-Tetramethyl-2-hexadecen-1-ol, 3-hexadecene and Phthalic acid. In terms of antibacterial activity, <i>C. racemosa</i> has promising antibacterial potential against aquatic pathogens <i>Aeromonas hydrophila, Aeromonas veronii</i> and <i>Aeromonas salmonicida</i>. Further evaluation studies focusing aquatic related aspects would reveal the novel bioproperties and applications of <i>C. racemosa</i>.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Evaluation of phytochemical screening, pigment content, in vitro antioxidant, antibacterial potential and GC-MS metabolite profiling of green seaweed <i>Caulerpa racemosa</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-21 01:33:24.365905","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"antibacterial activity; antioxidant activity; bioactive compounds; GC-MS; seaweed","OtherDescriptors":null,"Notes":null,"AnaPub":2023,"MonPub":null,"DateUpdate":"2025-09-18","DateCreate":"2023-10-02","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:000997081600001","VABBcode":null,"OpenAcc":1,"DOI":"10.3390/md21050278"},"refs":null,"anarec":{"AnaID":367660,"PubliDate":2023,"Pagination":"278","XtraPublOfAnaID":null,"ISBN":null,"Volume":"21","Issue":"5","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":113252,"SerRR":"Marine Drugs. 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