{"refrec":{"BRefID":367728,"RR":"<b>Hermans, C.; De Mol, M.L.; Mispelaere, M.; De Rop, A.-S.; Rombaut, J.; Nusayr, T.; Creamer, R.; De Maeseneire, S.L.; Soetaert, W.K.; Hulpiau, P.</b> (2023). MariClus: your one-stop platform for information on marine natural products, their gene clusters and producing organisms. <i>Mar. Drugs 21(8)</i>: 449. <a href=\"https://dx.doi.org/10.3390/md21080449\" target=\"_blank\">https://dx.doi.org/10.3390/md21080449</a>","BEntID":365453,"PublicFlag":1,"CheckedFlag":1,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Mar. Drugs 21(8)</i>: 449. <a href=\"https://dx.doi.org/10.3390/md21080449\" target=\"_blank\">https://dx.doi.org/10.3390/md21080449</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Hermans, C.; De Mol, M.L.; Mispelaere, M.; De Rop, A.-S.; Rombaut, J.; Nusayr, T.; Creamer, R.; De Maeseneire, S.L.; Soetaert, W.K.; Hulpiau, P.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Hermans, C. <i>et al.</i>","Englishabstract":"Background: The marine environment hosts the vast majority of living species and marine microbes that produce natural products with great potential in providing lead compounds for drug development. With over 70% of Earth’s surface covered in water and the high interaction rate associated with liquid environments, this has resulted in many marine natural product discoveries. Our improved understanding of the biosynthesis of these molecules, encoded by gene clusters, along with increased genomic information will aid us in uncovering even more novel compounds. Results: We introduce MariClus (https://www.mariclus.com), an online user-friendly platform for mining and visualizing marine gene clusters. The first version contains information on clusters and the predicted molecules for over 500 marine-related prokaryotes. The user-friendly interface allows scientists to easily search by species, cluster type or molecule and visualize the information in table format or graphical representation. Conclusions: This new online portal simplifies the exploration and comparison of gene clusters in marine species for scientists and assists in characterizing the bioactive molecules they produce. MariClus integrates data from public sources, like GenBank, MIBiG and PubChem, with genome mining results from antiSMASH. This allows users to access and analyze various aspects of marine natural product biosynthesis and diversity.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"MariClus: your one-stop platform for information on marine natural products, their gene clusters and producing organisms","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-04-21 01:33:24.537789","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"MariClus database; marine prokaryotes; genome mining; gene clusters; natural product discovery","OtherDescriptors":null,"Notes":null,"AnaPub":2023,"MonPub":null,"DateUpdate":"2025-09-18","DateCreate":"2023-10-02","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":"WOS:001056759400001","VABBcode":null,"OpenAcc":1,"DOI":"10.3390/md21080449"},"refs":null,"anarec":{"AnaID":367728,"PubliDate":2023,"Pagination":"449","XtraPublOfAnaID":null,"ISBN":null,"Volume":"21","Issue":"8","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":113252,"SerRR":"Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel.  ISSN 1660-3397; e-ISSN 1660-3397","StandardTitleSer":"Marine Drugs","ISSN":"1660-3397","AbbrevSer":"Mar. Drugs","StandardTitleMon":null,"StartPage":449,"Pages":null,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"Hermans","Firstname":"Cedric","Initials":"C.","Affiliation":"Bioinformatics Knowledge Center (BiKC), Campus Brugge Station, Howest University of Applied Sciences","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":542619,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":"0000-0002-9310-1876","PersID":44123,"InsID":null},{"AutName":"De Mol","Firstname":"Maarten","Initials":"M.L.","Affiliation":"Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":450795,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"InBio.be","InsFSN":"Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Biotechnologie; Centre for Industrial biotechnology and biocatalysis","ORCID":"0000-0002-9788-8688","PersID":40470,"InsID":8445},{"AutName":"Mispelaere","Firstname":"Marieke","Initials":"M.","Affiliation":"Bioinformatics Knowledge Center (BiKC), Campus Brugge Station, Howest University of Applied Sciences","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":542621,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":"0009-0005-3004-9424","PersID":44124,"InsID":null},{"AutName":"De Rop","Firstname":"Anne-Sofie","Initials":"A.-S.","Affiliation":"Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":490134,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"InBio.be","InsFSN":"Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Biotechnologie; Centre for Industrial biotechnology and biocatalysis","ORCID":"0000-0003-0775-5185","PersID":41227,"InsID":8445},{"AutName":"Rombaut","Firstname":"Jeltien","Initials":"J.","Affiliation":"Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":490135,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"InBio.be","InsFSN":"Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Biotechnologie; Centre for Industrial biotechnology and biocatalysis","ORCID":"0000-0003-2955-2098","PersID":41228,"InsID":8445},{"AutName":"Nusayr","Firstname":"Tesneem","Initials":"T.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":542624,"OrderNr":6,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Creamer","Firstname":"Rebecca","Initials":"R.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":542625,"OrderNr":7,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"De Maeseneire","Firstname":"Sofie","Initials":"S.L.","Affiliation":"Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":450797,"OrderNr":8,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"InBio.be","InsFSN":"Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Biotechnologie; Centre for Industrial biotechnology and biocatalysis","ORCID":"0000-0002-5314-1697","PersID":40472,"InsID":8445},{"AutName":"Soetaert","Firstname":"Wim","Initials":"W.K.","Affiliation":"Centre for Industrial Biotechnology and Biocatalysis (InBio.be), Department of Biotechnology, Faculty of Bioscience Engineering, Ghent University","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":450798,"OrderNr":9,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"InBio.be","InsFSN":"Universiteit Gent; Faculteit Bio-ingenieurswetenschappen; Vakgroep Biotechnologie; Centre for Industrial biotechnology and biocatalysis","ORCID":"0000-0002-7312-1941","PersID":15349,"InsID":8445},{"AutName":"Hulpiau","Firstname":"Paco","Initials":"P.","Affiliation":"BioInformatics Knowledge Center (BiKC), Campus Station Brugge, Howest University of Applied Sciences","Discriminator":null,"CorporateFlag":0,"BEntID":365453,"AutID":490139,"OrderNr":10,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":"0000-0002-6692-2150","PersID":37259,"InsID":null}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":null,"BEntPrivate":null,"availability":[{"BInstID":393036,"LibID":36,"BRefID":367728,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"393036","RFID":null,"PaidValue":null,"Medium":"Server","Description":"VLIZ Open Access","Acronym":"VLIZ","Library":"Vlaams Instituut voor de Zee","DutchTerm":"Open access","URL":null,"ClassifID":53,"Classification":"Open access","ReqLink":null,"ClassifTypID":1,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":null,"InternalReq":0,"LoggedInReq":0,"Disclaimer":null,"DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":36,"FileFormID":6,"LendableFlag":1,"PublicFlag":1,"orderLib":"A","Notes":null,"AccConID":null,"AccessConstraint":null,"LicURL":null}],"litstyles":null,"thespers":null,"arch2discl":null,"SERpubls":[{"PublName":"Molecular Diversity Preservation International (MDPI)","City":"Basel"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":null,"geotermsASFA":null,"collections":[{"Collection":"OMA - Open Marien Archief","ShortName":"OMA"}],"conf":null,"proj":null,"Physdatasets":null,"spcols":{"222":{"SpName":"BMB - Belgische Mariene Bibliografie","SpColID":222,"ParSpColID":null,"TopParID":null,"ShortName":"BMB","URLLocation":null,"LibID":36,"OpenRepoFlag":null,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"BMB"},"221":{"SpName":"OMA - Open Marien Archief","SpColID":221,"ParSpColID":null,"TopParID":null,"ShortName":"OMA","URLLocation":null,"LibID":36,"OpenRepoFlag":1,"SpTypID":null,"TopParIDNotWebsite":null,"SpColPath":"OMA"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":365453,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":365453,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.3390/md21080449","externalID":"10.3390/md21080449","URLTypeCode":"DOI","URLID":120259,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":null,"taxterms":null,"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":null,"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"Bouchti, Zohra, Z.","newSesDate":{"date":"2023-10-02 08:01:42.533000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"Lyssens, Liesbeth, L.","updSesDate":{"date":"2025-09-18 16:34:52.817000","timezone_type":3,"timezone":"Europe/Brussels"}}}