Document of bibliographic reference 368148

BibliographicReference record

Type

Bibliographic resource

Type of document

Journal article

BibLvlCode

AS

Title

Genus Litophyton: a hidden treasure trove of structurally unique and diversely bioactive secondary metabolites

Abstract

Marine soft corals are prolific sources of various natural products that have served as a wealthy reservoir of diverse chemical scaffolds with potential as new drug leads. The genus Litophyton contains almost 100 species but only a small proportion of them has been chemically investigated, which calls for more attentions from global researchers. In the current work, 175 secondary metabolites have been discussed, drawing from published data spanning almost five decades, up to July 2023. The studied species of the genus Litophyton resided in various tropical and temperate regions and encompassed a broad range of biologically active natural products including terpenes, steroids, nitrogen-containing metabolites, lipids, and other metabolites. A wide spectrum of pharmacological effects of these compounds had been evaluated, such as cytotoxic, antiviral, antibacterial, antifungal, anti-malarial, antifeedant, anti-inflammatory, molluscicidal, PTP1B inhibitory, insect growth inhibitory, and neuroprotective activities. This review aims to offer an up-to-date survey of the literature and provide a comprehensive understanding of the chemical structures, taxonomical distributions, and biological activities of the reported metabolites from the title genus whenever available.

WebOfScience code

https://www.webofscience.com/wos/woscc/full-record/WOS:001122379000001

Bibliographic citation

Yan, X.-Y.; Zhang, L.; Yang, Q.-B.; Ge, Z.-Y.; Liang, L.-F.; Guo, Y.-W. (2023). Genus Litophyton: a hidden treasure trove of structurally unique and diversely bioactive secondary metabolites. Mar. Drugs 21(10): 523. https://dx.doi.org/10.3390/md21100523

Topic

Marine

Is peer reviewed

true

Access rights

open access

Is accessible for free

true