{"refrec":{"BRefID":381446,"RR":"<b>Neubauer, C.; Kantnerová, K.; Lamothe, A.; Savarino, J.; Hilkert, A.; Juchelka, D.; Hinrichs, K.-U.; Elvert, M.; Heuer, V.B.; Elsner, M.; Bakkour, R.; Julien, M.; Öztoprak, M.; Schouten, S.; Hattori, S.; Dittmar, T.</b> (2023). Discovering nature’s fingerprints: isotope ratio analysis on bioanalytical mass spectrometers. <i>Journal of the American Society for Mass Spectrometry 34(4)</i>: 525-537. <a href=\"https://dx.doi.org/10.1021/jasms.2c00363\" target=\"_blank\">https://dx.doi.org/10.1021/jasms.2c00363</a>","BEntID":379187,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Journal of the American Society for Mass Spectrometry 34(4)</i>: 525-537. <a href=\"https://dx.doi.org/10.1021/jasms.2c00363\" target=\"_blank\">https://dx.doi.org/10.1021/jasms.2c00363</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Neubauer, C.; Kantnerová, K.; Lamothe, A.; Savarino, J.; Hilkert, A.; Juchelka, D.; Hinrichs, K.-U.; Elvert, M.; Heuer, V.B.; Elsner, M.; Bakkour, R.; Julien, M.; Öztoprak, M.; Schouten, S.; Hattori, S.; Dittmar, T.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Neubauer, C. <i>et al.</i>","Englishabstract":"For a generation or more, the mass spectrometry that developed at the frontier of molecular biology was worlds apart from isotope ratio mass spectrometry, a label-free approach done on optimized gas-source magnetic sector instruments. Recent studies show that electrospray-ionization Orbitraps and other mass spectrometers widely used in the life sciences can be fine-tuned for high-precision isotope ratio analysis. Since isotope patterns form everywhere in nature based on well-understood principles, intramolecular isotope measurements allow unique insights into a fascinating range of research topics. This perspective introduces a wider readership to current topics in stable isotope research with the aim to discuss how soft-ionization mass spectrometry coupled with ultra-high mass resolution can enable long-envisioned progress. 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