{"refrec":{"BRefID":396833,"RR":"<b>Batista, R.A.; Wang, L.; Bogaert, K.A.; Coelho, S.M.</b> (2024). Insights into the molecular bases of multicellular development from brown algae. <i>Development 151(20)</i>: dev203004. <a href=\"https://dx.doi.org/10.1242/dev.203004\" target=\"_blank\">https://dx.doi.org/10.1242/dev.203004</a>","BEntID":394622,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Development 151(20)</i>: dev203004. <a href=\"https://dx.doi.org/10.1242/dev.203004\" target=\"_blank\">https://dx.doi.org/10.1242/dev.203004</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Batista, R.A.; Wang, L.; Bogaert, K.A.; Coelho, S.M.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Batista, R.A. <i>et al.</i>","Englishabstract":"<span style=\"background-color:rgb(255,255,255);color:rgb(26,26,26);\">The transition from simple to complex multicellularity represents a major evolutionary step that occurred in only a few eukaryotic lineages. Comparative analyses of these lineages provide insights into the molecular and cellular mechanisms driving this transition, but limited understanding of the biology of some complex multicellular lineages, such as brown algae, has hampered progress. This Review explores how recent advances in genetic and genomic technologies now allow detailed investigations into the molecular bases of brown algae development. We highlight how forward genetic techniques have identified mutants that enhance our understanding of pattern formation and sexual differentiation in these organisms. Additionally, the existence and nature of morphogens in brown algae and the potential influence of the microbiome in key developmental processes are examined. Outstanding questions, such as the identity of master regulators, the definition and characterization of cell types, and the molecular bases of developmental plasticity are discussed, with insights into how recent technical advances could provide answers. Overall, this Review highlights how brown algae are emerging as alternative model organisms, contributing to our understanding of the evolution of multicellular life and the diversity of body plans.</span>","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Insights into the molecular bases of multicellular development from brown algae","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2025-01-29 01:33:10.554531","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"ectocarpus, algal genetics, brown algae, multicellularity ","OtherDescriptors":null,"Notes":null,"AnaPub":2024,"MonPub":null,"DateUpdate":"2025-01-22","DateCreate":"2024-11-20","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0,"DOI":"10.1242/dev.203004"},"refs":null,"anarec":{"AnaID":396833,"PubliDate":2024,"Pagination":"dev203004","XtraPublOfAnaID":null,"ISBN":null,"Volume":"151","Issue":"20","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42786,"SerRR":"Development. 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