{"refrec":{"BRefID":405198,"RR":"<b>Khaliq, S.; Jochmann, M.A.; Hesse, T.; Nachev, M.; Sures, B.; Riekenberg, P.M.; van der Meer, M.T.J.; Schmidt, T.C.</b> (2024). Compound-specific isotope analysis of amino acids for aquatic systems – Problems, challenges, solutions: A review. <i>Trends Anal. Chem. 181</i>: 118038. <a href=\"https://dx.doi.org/10.1016/j.trac.2024.118038\" target=\"_blank\">https://dx.doi.org/10.1016/j.trac.2024.118038</a>","BEntID":402993,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Trends Anal. Chem. 181</i>: 118038. <a href=\"https://dx.doi.org/10.1016/j.trac.2024.118038\" target=\"_blank\">https://dx.doi.org/10.1016/j.trac.2024.118038</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Khaliq, S.; Jochmann, M.A.; Hesse, T.; Nachev, M.; Sures, B.; Riekenberg, P.M.; van der Meer, M.T.J.; Schmidt, T.C.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Khaliq, S. <i>et al.</i>","Englishabstract":"<span style=\"color:rgb(31,31,31);\">Compound-specific isotope analysis of individual amino acids (AAs) is a promising method for characterizing resource flow and transformation in aquatic systems, encompassing microbial domains to macroscopic consumers. This review delves into two key areas of research concerning AAs in aquatic ecosystems. Firstly, carbon isotope analysis is employed to explore carbon sources assimilated for AAs synthesis, and secondly, nitrogen isotope analysis is used to clarify ecosystem baselines and trophic dynamics of organisms. Surprisingly, literature provides limited discussions on the limitations or critical challenges faced during AAs isotope analysis over the past decade. To address this gap, this review focuses on challenges encountered in method development, sample preparation, and technical aspects, including instrumental design, and δ</span><sup>13</sup><span style=\"color:rgb(31,31,31);\">C and δ</span><sup>15</sup><span style=\"color:rgb(31,31,31);\">N analysis of AAs. Recommendations are provided to increase the accuracy and reliability. The review also highlights the significance of comprehensive understanding and detailed methodology to address challenges during AA isotope analysis in aquatic systems.</span>","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Compound-specific isotope analysis of amino acids for aquatic systems – Problems, challenges, solutions: A review","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-04 01:31:54.528408","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Compound-specific stable isotope analysis; CSIA; Amino acids; Aquatic systems; GC-IRMS; LC-IRMS","OtherDescriptors":null,"Notes":null,"AnaPub":2024,"MonPub":null,"DateUpdate":"2025-01-07","DateCreate":"2025-01-07","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":1,"DOI":"10.1016/j.trac.2024.118038"},"refs":null,"anarec":{"AnaID":405198,"PubliDate":2024,"Pagination":"118038","XtraPublOfAnaID":null,"ISBN":null,"Volume":"181","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":45433,"SerRR":"Trends in Analytical Chemistry. 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