{"refrec":{"BRefID":4324,"RR":"<b>Carrillo, M.; Mañanós, E.; Sorbera, L.; Milonas, C.C.; Cuisser, B.; Zohar, J.; Zanuy, S.</b> (2000). Effects of sustained administration of GnRHa on gonadotropin-II (GTH-II) and gonadal steroid levels in adult male sea bass (Dicentrarchus labrax), <b><i>in</i></b>: Norberg, B. <i>et al.</i> (Ed.) <i>Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999.</i> pp. 393-395","BEntID":4324,"PublicFlag":1,"CheckedFlag":0,"wosflag":null,"vabbflag":null,"RefStringPartII":", <b><i>in</i></b>: Norberg, B. <i>et al.</i> <i>Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. International Symposium on the Reproductive Physiology of Fish,</i> 6: pp. 393-395","DocTypID":17,"DocType":"Book chapters","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Carrillo, M.; Mañanós, E.; Sorbera, L.; Milonas, C.C.; Cuisser, B.; Zohar, J.; Zanuy, S.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Carrillo, M. <i>et al.</i>","Englishabstract":"Spermiating European sea bass, were treated either with GnRHa injection in saline (I; 25 µg Kg super(-1) body weight [BW]) or one of three types of controlled-release gonadotropin-releasing hormone agonist (GnRHa)-delivery systems: a fast releasing implant (EVAc; 100 µg Kg super(-1)), a slower-releasing implant (EVSL; 100 µg Kg super(-1)) and biodegradable micro spheres (M; 50 µg Kg super(-1)). Resulting changes in plasma gonadotropin II (GTH-II), Testosterone (T), 11-Ketotestosterone (11-KT) and 17,20 beta -dihydroxy-4-pregnen-3-one (17,20 beta -P) were correlated with changes in milt production previously reported. The GnRHa-delivery systems, M and EVSL, induced a sustained elevation of plasma GTH-II for 35 and 44 days, respectively, while I and M maintained higher GTH-II plasma levels for 2 and 14 days, respectively. Plasma 11-KT levels in treated fish did not differ from those of controls and declined gradually during the experimental period. Plasma T levels of treated fish were also similar to controls remaining elevated during the first 14 days of treatment and declining thereafter except for M and EVSL which exhibited high levels of T for an extra week. Moreover, these were the only two groups with an extended period of spermiation for 35 days. Plasma 17,20 beta -P levels were unchanged after GnRHa treatment except for M and EVSL which showed a significant increase of this progestagen on day 7. In addition, only the EVSL group exhibited another significant peak of 17,20 beta -P on day 28. This study demonstrated that the GnRHa-delivery systems induced a sustained but different elevation of plasma GTH-II levels in sea bass depending on the type of delivery system used, which resulted in a corresponding and long term enhancement of milt production. The possible role of androgens and progestagens is also discussed.","AbstractOtherLang":null,"BibLvlCode":"AMS","StandardTitle":"Effects of sustained administration of GnRHa on gonadotropin-II (GTH-II) and gonadal steroid levels in adult male sea bass (Dicentrarchus labrax)","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2025-07-08 01:30:35.439685","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2000,"MonPub":null,"DateUpdate":"2001-11-14","DateCreate":"2000-11-08","SecASFANote":null,"ConfID":null,"PeerRev":0,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":4324,"PubliDate":2000,"Pagination":"393-395","XtraPublOfAnaID":null,"ISBN":"82-7461-048-2","Volume":"6","Issue":null,"BRefMon":4111,"BRefMonRR":"<b>Norberg, B. <i>et al.</i></b> (2000). 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