{"refrec":{"BRefID":437423,"RR":"<b>François, D.; Reichart, G.-J.; de Nooijer, L.J.</b> (2025). Open or closed: pH modulation and calcification by foraminifera. <i>Science Advances 11(18)</i>: eadq8425. <a href=\"https://dx.doi.org/10.1126/sciadv.adq8425\" target=\"_blank\">https://dx.doi.org/10.1126/sciadv.adq8425</a>","BEntID":435254,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":0,"RefStringPartII":". <i>Science Advances 11(18)</i>: eadq8425. <a href=\"https://dx.doi.org/10.1126/sciadv.adq8425\" target=\"_blank\">https://dx.doi.org/10.1126/sciadv.adq8425</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"François, D.; Reichart, G.-J.; de Nooijer, L.J.","OrigTitleTranslFlag":0,"Authorstringtrunc":"François, D.; Reichart, G.-J.; de Nooijer, L.J.","Englishabstract":"<span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\">Marine calcifying organisms precipitate their shells either in equilibrium with seawater or under strict biological control. Here, we show that these two options represent two ends of a spectrum. In species with a more “closed” system, rates of H</span><sup>+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\"> removal and Ca</span><sup>2+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\"> uptake are high and exceed the amount of ions required for calcification. This explains the relatively low Mg/Ca of the calcite of this species by dilution of the [Mg</span><sup>2+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\">] in the calcifying fluid. Conversely, in species with a more open system, the H</span><sup>+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\"> and Ca</span><sup>2+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\"> fluxes are lower, with more seawater exchanged between the environment and calcifying fluid, explaining the relatively high Mg/Ca in these foraminifera. In either of these species, mitochondria were found to be located at the site where the Ca</span><sup>2+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\">/H</span><sup>+</sup><span style=\"background-color:rgb(246,246,246);color:rgb(51,51,51);\"> exchange takes place and the mitochondrial density aligned with the rate of pumping. These findings highlight the crucial role of transmembrane transporters and mitochondria in foraminifera calcification and explain the species-specific elemental signatures.</span>","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Open or closed: pH modulation and calcification by foraminifera","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-02-04 01:32:58.705782","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":2025,"MonPub":null,"DateUpdate":"2026-01-28","DateCreate":"2026-01-28","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":1,"DOI":"10.1126/sciadv.adq8425"},"refs":null,"anarec":{"AnaID":437423,"PubliDate":2025,"Pagination":"eadq8425","XtraPublOfAnaID":null,"ISBN":null,"Volume":"11","Issue":"18","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":248966,"SerRR":"Science Advances. 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ISSN 2375-2548; e-ISSN 2375-2548","StandardTitleSer":"Science Advances","ISSN":"2375-2548","AbbrevSer":null,"StandardTitleMon":null,"StartPage":null,"Pages":null,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":null,"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"François","Firstname":"Daniel","Initials":"D.","Affiliation":"OCS","Discriminator":null,"CorporateFlag":0,"BEntID":435254,"AutID":616423,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"NIOZ","InsFSN":"Koninklijk Nederlands Instituut voor Onderzoek der Zee","ORCID":"0000-0003-0173-6936","PersID":46189,"InsID":397},{"AutName":"Reichart","Firstname":"Gert-Jan","Initials":"G.-J.","Affiliation":"OCS","Discriminator":null,"CorporateFlag":0,"BEntID":435254,"AutID":205637,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"OCS","InsFSN":"Koninklijk Nederlands Instituut voor Onderzoek der Zee; Ocean Sciences","ORCID":"0000-0002-7256-2243","PersID":15347,"InsID":13654},{"AutName":"de Nooijer","Firstname":"Lennart","Initials":"L.J.","Affiliation":"OCS","Discriminator":null,"CorporateFlag":0,"BEntID":435254,"AutID":205638,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":"OCS","InsFSN":"Koninklijk Nederlands Instituut voor Onderzoek der Zee; Ocean Sciences","ORCID":"0000-0002-8949-8874","PersID":29875,"InsID":13654}],"mapdetails":null,"datasets":null,"monographs":null,"monparts":null,"serparts":null,"BEntOpen":435254,"BEntPrivate":null,"availability":[{"BInstID":419061,"LibID":2779,"BRefID":437423,"EmbargoDate":null,"FullEmbargoDate":null,"PhysMedID":16,"hasOCRd":1,"ShelfLocCode":"419061","RFID":null,"PaidValue":null,"Medium":"Server","Description":null,"Acronym":null,"Library":"NIOZ","DutchTerm":null,"URL":null,"ClassifID":260,"Classification":"NIOZ Open Repository","ReqLink":null,"ClassifTypID":1,"URLLocation":"https://www.vliz.be/imisdocs/publications/","SubDir":1,"InternalReq":null,"LoggedInReq":null,"Disclaimer":"Disclaimer_NIOZ","DutchDisclaimer":null,"FileFormat":".pdf","FileDescr":"pdf","InsPub":1,"InsID":397,"FileFormID":6,"LendableFlag":null,"PublicFlag":1,"orderLib":"NIOZ","Notes":null,"AccConID":21,"AccessConstraint":"Attribution (CC BY)","LicURL":"https://creativecommons.org/licenses/by/4.0/"}],"litstyles":null,"thespers":null,"arch2discl":805,"SERpubls":[{"PublName":"AAAS","City":"New York"}],"MONpubls":null,"pictures":[],"thestermsPath":null,"thestermsASFA":null,"taxtermsASFA":null,"geotermsASFA":null,"collections":null,"conf":null,"proj":null,"Physdatasets":null,"spcols":{"805":{"SpName":"Koninklijk Nederlands Instituut voor Onderzoek der Zee","SpColID":805,"ParSpColID":null,"TopParID":null,"ShortName":"NIOZ","URLLocation":"https://www.vliz.be/imis/nioz/imis.php?refid=","LibID":2779,"OpenRepoFlag":1,"SpTypID":1,"TopParIDNotWebsite":null,"SpColPath":"NIOZ"}},"doi":null,"publs":null,"serparttypes":null,"monauthors":null,"MParts":null,"SParts":null,"hLibs":null,"langs":[{"BEntID":435254,"AbstractFlag":0,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"},{"BEntID":435254,"AbstractFlag":1,"LangID":15,"LangCode":"en","Lang":"English","DutchTerm":"Engels","LangCodeExtended":"eng"}],"urls":[{"URL":"https://dx.doi.org/10.1126/sciadv.adq8425","externalID":"10.1126/sciadv.adq8425","URLTypeCode":"DOI","URLID":157783,"URLTypID":13,"URLType":"DOI","URLPrefix":"http://dx.doi.org/"}],"thesterms":null,"taxterms":null,"geoterms":null,"othterms":null,"asfacodes":null,"asfa2codes":null,"thestermsFRIS":null,"taxtermsFRIS":null,"geotermsFRIS":null,"othtermsFRIS":null,"resmessage":"","complete":1,"sessions":{"newSesName":"daan.van.loon@nioz.nl","newSesDate":{"date":"2026-01-28 14:36:52.267000","timezone_type":3,"timezone":"Europe/Brussels"},"updSesName":"daan.van.loon@nioz.nl","updSesDate":{"date":"2026-01-28 14:36:52.267000","timezone_type":3,"timezone":"Europe/Brussels"}}}