{"refrec":{"BRefID":440608,"RR":"<b>Speleers, B.; Stouthandel, M.E.J.; Vakaet, V.; Paelinck, L.; Schoepen, M.; Van Greveling, A.; Van Esch, A.; Wéra, A.-C.; Remouchamps, V.; Van Hoof, T.; Veldeman, L.; De Gersem, W.; De Neve, W.</b> (2026). Organ at risk sparing by non-coplanar prone breast radiotherapy on Halcyon/Ethos linacs utilizing breast couch slewing. <i>NPG Scientific Reports article in press</i>. <a href=\"https://dx.doi.org/10.1038/s41598-026-54571-4\" target=\"_blank\">https://dx.doi.org/10.1038/s41598-026-54571-4</a>","BEntID":438442,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>NPG Scientific Reports article in press</i>. <a href=\"https://dx.doi.org/10.1038/s41598-026-54571-4\" target=\"_blank\">https://dx.doi.org/10.1038/s41598-026-54571-4</a>","DocTypID":8,"DocType":"Journal article","MarineFlag":0,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Speleers, B.; Stouthandel, M.E.J.; Vakaet, V.; Paelinck, L.; Schoepen, M.; Van Greveling, A.; Van Esch, A.; Wéra, A.-C.; Remouchamps, V.; Van Hoof, T.; Veldeman, L.; De Gersem, W.; De Neve, W.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Speleers, B. <i>et al.</i>","Englishabstract":"<span style=\"background-color:rgb(255,255,255);color:rgb(34,34,34);\">Organ at risk (OAR)-dose reductions are needed to minimize radiation toxicity in settings with high OAR-doses, like adjuvant breast and lymph node radiotherapy. Non-coplanar techniques, combined with prone positioning and deep inspiration breath hold (DIBH) techniques, could accomplish this. A planning study was performed in patients requiring left-side adjuvant breast and axillary/periclavicular lymph node irradiation (</span><i>n</i><span style=\"background-color:rgb(255,255,255);color:rgb(34,34,34);\"> = 8). Simulation was performed in prone crawl position using DIBH. Coplanar and non-coplanar short-arc VMAT plans were compared. Non-coplanar plans featured ≤ 20° angular separation between planes. Feasibility was tested using a CAD model, including a prone crawl breast couch positioned in an up to 20° angle (transverse plane) with the couchtop. Non-coplanar techniques can further reduce radiation exposure. Adding beams in planes with ± 15° to ± 20° angular separation with the transverse plane yielded &gt; 20% mean-dose reductions simultaneously to heart, lungs and esophagus, compared to coplanar plans. Plans with ≤ ± 20° angular separation with the transverse plane proved feasible on linacs lacking couch isocenter rotations. Angular separation of ± 15° seems the best compromise between OAR-sparing and technical challenges. Non-coplanar radiotherapy options yielded superior OAR sparing compared to coplanar techniques in patients requiring adjuvant breast and lymph node irradiation and should be considered for improved radiation toxicity prevention.</span>","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Organ at risk sparing by non-coplanar prone breast radiotherapy on Halcyon/Ethos linacs utilizing breast couch slewing","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2026-06-18 01:39:04.630586","timezone_type":1,"timezone":"+02:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":"Organ at risk sparing; Treatment planning; Deep inspiration breath hold","OtherDescriptors":null,"Notes":null,"AnaPub":2026,"MonPub":null,"DateUpdate":"2026-06-15","DateCreate":"2026-06-15","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":0,"WoScode":null,"VABBcode":null,"OpenAcc":0,"DOI":"10.1038/s41598-026-54571-4"},"refs":null,"anarec":{"AnaID":440608,"PubliDate":2026,"Pagination":null,"XtraPublOfAnaID":null,"ISBN":null,"Volume":"article in press","Issue":null,"BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":208093,"SerRR":"Scientific Reports (Nature Publishing Group). 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