Document of bibliographic reference 71842

BibliographicReference record

Type

Bibliographic resource

Type of document

Journal article

BibLvlCode

AS

Title

Development and validation of an analytical method for detection of estrogens in water

Abstract

An analytical procedure enabling routine analysis of four environmental estrogens at concentrations below 1 ng L^–1 in estuarine water samples has been developed and validated. The method includes extraction of water samples using solid-phase extraction discs and detection by gas chromatography (GC) with tandem mass spectrometry (MS–MS) in electron-impact (EI) mode. The targeted estrogens included 17 alpha- and 17 beta-estradiol (aE2, bE2), estrone (E1), and 17 alpha-ethinylestradiol (EE2), all known environmental endocrine disruptors. Method performance characteristics, for example trueness, recovery, calibration, precision, accuracy, limit of quantification (LOQ), and the stability of the compounds are presented for each of the selected estrogens. Application of the procedure to water samples from the Scheldt estuary (Belgium – The Netherlands), a polluted estuary with reported incidences of environmental endocrine disruption, revealed that E1 was detected most frequently at concentrations up to 7 ng L^–1. aE2 was detected once only and concentrations of bE2 and EE2 were below the LOQ

WebOfScience code

https://www.webofscience.com/wos/woscc/full-record/WOS:000229189500015

Bibliographic citation

Noppe, H.; De Wasch, K.; Poelmans, S.; Van Hoof, N.; Verslycke, T.; Janssen, C.R.; De Brabander, H. (2005). Development and validation of an analytical method for detection of estrogens in water. Anal. Bioanal. Chem. 382(1): 91-98. dx.doi.org/10.1007/s00216-005-3174-8

Topic

Marine

Is peer reviewed

true