{"refrec":{"BRefID":77357,"RR":"<b>de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E.</b> (1995). Short term fasting does not aggravate immunosuppression in harbour seals (<i>Phoca vitulina</i>) with high body burdens of organochlorines. <i>Chemosphere 31(10)</i>: 4289-4306","BEntID":72956,"PublicFlag":1,"CheckedFlag":0,"wosflag":1,"vabbflag":1,"RefStringPartII":". <i>Chemosphere 31(10)</i>: 4289-4306","DocTypID":8,"DocType":"Journal article","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E.","OrigTitleTranslFlag":0,"Authorstringtrunc":"de Swart, R.L. <i>et al.</i>","Englishabstract":"Two groups of 11 harbour seals (<i>Phoca vitulina</i>) with different body burdens of organochlorines were subjected to an experimental 15-day fasting period, during which they lost an average 16.5% of their body weights. Blood levels of the most persistent organochlorines showed an approximate twofold increase, while levels of aryl hydrocarbon receptor-binding organochlorines remained largely unaffected. Few differences in immunological parameters were observed between the two dietary groups. Numbers of circulating lymphocytes dropped to about 65% of the initial values and NK cell activity showed a slight increase in both groups. Mitogen- and antigen-induced lymphoproliferative responses of the Baltic group of seals remained within normal ranges. These results suggest that relatively short-term fasting periods do not present an additional immunotoxicological risk to seals with high body burdens of organochlorines.","AbstractOtherLang":null,"BibLvlCode":"AS","StandardTitle":"Short term fasting does not aggravate immunosuppression in harbour seals (<i>Phoca vitulina</i>) with high body burdens of organochlorines","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":1995,"MonPub":null,"DateUpdate":"2019-08-27","DateCreate":"2005-10-24","SecASFANote":null,"ConfID":null,"PeerRev":1,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":77357,"PubliDate":1995,"Pagination":"4289-4306","XtraPublOfAnaID":null,"ISBN":null,"Volume":"31","Issue":"10","BRefMon":null,"BRefMonRR":null,"BRefXtra":null,"BRefXtraRR":null,"SerBRefID":42564,"SerRR":"Chemosphere. Elsevier: Oxford.  ISSN 0045-6535; e-ISSN 1879-1298","StandardTitleSer":"Chemosphere","ISSN":"0045-6535","AbbrevSer":"Chemosphere","StandardTitleMon":null,"StartPage":4289,"Pages":18,"ToPubliDate":null,"BRefBibLvlCode":"S","SerNotes":null},"monrec":null,"serrec":null,"relations":[{"YBRefID":77358,"RefStrFull":"<b>de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E.</b> (1995). Short term fasting does not aggravate immunosuppression in harbour seals (<i>Phoca vitulina</i>) with high body burdens of organochlorines, <b><i>in</i></b>: de Swart, R.L. <i>Impaired immunity in seals exposed to bioaccumulated environmental contaminants = Immuunsuppressie in zeehonden blootgesteld aan in de voedselketen geaccumuleerde milieuvervuilende stoffen.</i> pp. 95-110","RelID":4,"Relation":"Related to","StandardTitle":"Short term fasting does not aggravate immunosuppression in harbour seals (<i>Phoca vitulina</i>) with high body burdens of organochlorines"}],"relationsRev":null,"addrec":null,"othpubs":null,"ownerships":null,"authors":[{"AutName":"de Swart","Firstname":"Rik","Initials":"R.L.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":72956,"AutID":19241,"OrderNr":1,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Ross","Firstname":"Peter Stuart","Initials":"P.S.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":72956,"AutID":19243,"OrderNr":2,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Timmerman","Firstname":"Helga","Initials":"H.H.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":72956,"AutID":55891,"OrderNr":3,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Hijman","Firstname":"Willy","Initials":"W.C.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":72956,"AutID":55966,"OrderNr":4,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"De Ruiter","Firstname":"Elze","Initials":"E.","Affiliation":null,"Discriminator":null,"CorporateFlag":0,"BEntID":72956,"AutID":55967,"OrderNr":5,"DegrID":null,"EditorFlag":0,"CorrespFlag":0,"IllustratorFlag":0,"ReviserFlag":0,"TranslatorFlag":0,"InsAcronym":null,"InsFSN":null,"ORCID":null,"PersID":null,"InsID":null},{"AutName":"Liem","Firstname":"A.K. 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