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The results show the presence of at least 2 different enzymes, acetylcholinesterase and butyrylcholinesterase, with high activities in brain, muscle and liver. No variation was observed in relation to sex or size. The activity of both acetylcholinesterase and butyrylcholinesterase was depressed in nearshore stations along the transect and no variation was observed around the drilling site. The K sub(m) of acetylcholinesterase from muscle of dab varied along the transect. 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