{"refrec":{"BRefID":8328,"RR":"<b>Allen, T.J.A.; Rouot, B.</b> (1995). Cyclic nucleotide homeostasis and axonal G proteins in the squid <i>Loligo forbesi</i>, <b><i>in</i></b>: Abbott, N.J. <i>et al.</i> (Ed.) <i>Cephalopod neurobiology: neuroscience studies in squid, octopus and cuttlefish.</i> pp. 35-52","BEntID":8328,"PublicFlag":1,"CheckedFlag":0,"wosflag":null,"vabbflag":null,"RefStringPartII":", <b><i>in</i></b>: Abbott, N.J. <i>et al.</i> <i>Cephalopod neurobiology: neuroscience studies in squid, octopus and cuttlefish.</i> pp. 35-52","DocTypID":17,"DocType":"Book chapters","MarineFlag":1,"FreshFlag":0,"BrackishFlag":0,"TerrestrialFlag":0,"Authorstring":"Allen, T.J.A.; Rouot, B.","OrigTitleTranslFlag":0,"Authorstringtrunc":"Allen, T.J.A.; Rouot, B.","Englishabstract":"This chapter reviews studies on signal: transduction coupling in the squid giant axon and its associated Schwann cell sheath, and the role of cyclic nucleotides and G-proteins in this coupling. The cAMP content of the axon is increased by external application of serotonin (5HT), and this effect is modulated by [Ca²+]<sub>i</sub> and is dependent on internal GTP; membrane G-proteins are implicated in the coupling. Lowering [Mg²+]<sub>i</sub> attenuates 5HT -evoked adenylate cyclase activity. The giant axon provides too little G-protein for analysis, but it has been possible to demonstrate G-proteins in the richer source of squid optic lobes. The cGMP content of the axon is increased by carbachol, and by nitroprusside, an agent activating cGMP synthesis. The role of G-proteins in Schwann cell-axon signalling is discussed.","AbstractOtherLang":null,"BibLvlCode":"AM","StandardTitle":"Cyclic nucleotide homeostasis and axonal G proteins in the squid <i>Loligo forbesi</i>","OrigTitleLangCode":"en","OrigTitleLangCodeExtended":"eng","OrigTitleLangID":15,"DateLastModified":{"date":"2024-12-10 01:33:17.368041","timezone_type":1,"timezone":"+01:00"},"UserAccessRight":null,"UserAccID":null,"AuthorKeywords":null,"OtherDescriptors":null,"Notes":null,"AnaPub":1995,"MonPub":null,"DateUpdate":"2001-05-07","DateCreate":"2001-05-07","SecASFANote":null,"ConfID":null,"PeerRev":null,"VlizCoreFlag":1,"WoScode":null,"VABBcode":null,"OpenAcc":0},"refs":null,"anarec":{"AnaID":8328,"PubliDate":1995,"Pagination":"35-52","XtraPublOfAnaID":null,"ISBN":"0-19-854790-0","Volume":null,"Issue":null,"BRefMon":8320,"BRefMonRR":"<b>Abbott, N.J.; Williamson, R.; Maddock, L. (Ed.)</b> (1995). Cephalopod neurobiology: Neuroscience studies in squid, octopus and cuttlefish. Oxford University Press: London. ISBN 0-19-854790-0. 542 pp. <a href=\"https://dx.doi.org/10.1093/acprof:oso/9780198547907.001.0001\" target=\"_blank\">https://dx.doi.org/10.1093/acprof:oso/9780198547907.001.0001</a>","BRefXtra":null,"BRefXtraRR":null,"SerBRefID":null,"SerRR":null,"StandardTitleSer":null,"ISSN":null,"AbbrevSer":null,"StandardTitleMon":"Cephalopod neurobiology: Neuroscience studies in squid, octopus and cuttlefish","StartPage":35,"Pages":18,"ToPubliDate":null,"BRefBibLvlCode":"M","SerNotes":null,"AutString":"Abbott, N.J.; Williamson, R.; Maddock, L. 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