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Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium
Bertanha, C.; Januário, A.; Alvarenga, T.; Pimenta, L.; Silva, M.; Cunha, W.; Pauletti, P. (2014). Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium. Mar. Drugs 12(6): 3608-3633. https://dx.doi.org/10.3390/md12063608
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, more
Peer reviewed article  

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Keyword
    Marine/Coastal
Author keywords
    ascidian secondary metabolites; structure elucidation; bioactivity; 13C-NMR spectral data; quinones; hydroquinones

Authors  Top 
  • Bertanha, C.
  • Januário, A.
  • Alvarenga, T.
  • Pimenta, L.
  • Silva, M.
  • Cunha, W.
  • Pauletti, P.

Abstract
    Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.

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