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A-nor steroids from the marine sponge, Clathria species = Steroid A-nor daripada Span Laut, Spesies Clathria
Sahidin, I.; Sabandar, S.W.; Wahyuni, W.; Hamsidi, R.; Malaka, M.H.; Sadarun, B.; Aslan, L.O. (2018). A-nor steroids from the marine sponge, Clathria species = Steroid A-nor daripada Span Laut, Spesies Clathria. Malaysian Journal of Analytical Sciences 22(3): 375-382. https://dx.doi.org/10.17576/mjas-2018-2203-02
In: Malaysian Journal of Analytical Sciences. Malaysian Analytical Sciences Society: Selangor. ISSN 1394-2506, more
Peer reviewed article  

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Keywords
Author keywords
    Clathria sp.; marine sponge; A-nor steroid; 3ß-(Butyryloxymethyl)-A-nor-5a-cholestane

Authors  Top 
  • Sahidin, I.
  • Sabandar, S.W.
  • Wahyuni, W.
  • Hamsidi, R.
  • Malaka, M.H.
  • Sadarun, B.
  • Aslan, L.O.

Abstract
    Chemical compounds classified as A-nor steroids (1–4) were isolated from a marine sponge of the Clathria sp., collected from Southeast Sulawesi, Indonesia. Of these, one new compound, clathruhoate (1) was elucidated as 3β-(butyryloxymethyl)-A-nor-5α-cholestane. All compounds were obtained using silica gel chromatography techniques and their structures were determined based on 1D and 2D NMR spectroscopic measurements and comparison with values from literature. Meanwhile, all compounds were inactive for antimicrobial activity.

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