The efficacy of a single intraperitoneal injection of either flumequine or oxytetracycline hydrochloride in prevention of outbreaks of atypical Aeromonas salmonicida infection in goldsinny wrasse, Ctenolabrus rupestris L., following stress
Samuelsen, O.B.; Ervik, A.; Torkildsen, L.; Bergh, Ø. (2002). The efficacy of a single intraperitoneal injection of either flumequine or oxytetracycline hydrochloride in prevention of outbreaks of atypical Aeromonas salmonicida infection in goldsinny wrasse, Ctenolabrus rupestris L., following stress. Aquacult. Int. 10(3): 257-264. https://dx.doi.org/10.1023/A:1022187627019
In: Aquaculture International. Springer: London. ISSN 0967-6120; e-ISSN 1573-143X, more
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| Keywords |
Aquatic organisms > Marine organisms > Fish > Marine fish
Diseases
Drugs
Efficiency
Ctenolabrus rupestris (Linnaeus, 1758) [WoRMS]
Marine/Coastal |
| Authors | | Top |
- Samuelsen, O.B., correspondent
- Ervik, A.
- Torkildsen, L.
- Bergh, Ø.
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| Abstract |
In this investigation, the efficacy of a single intraperitoneal injection of either flumequine or oxytetracycline hydrochloride to prevent outbreak of atypical Aeromonas salmonicida infection in goldsinny wrasse, Ctenolabrus rupestris, following stress was studied. Six groups of goldsinny wrasse, each of 50 individuals, were treated with an intraperitoneal injection of either propylene glycol : saline (50 : 50), 200 mg kg-1 of oxytetracycline or 50 mg kg-1 of flumequine dissolved in propylene glycol : saline (50 : 50). Three days following medication the fish in all groups were stressed by an intraperitoneal injection of prednisolone acetate (0.05 ml) and a rise in seawater temperature from 9 to 11 °C. Mortality was observed daily for 21 days. Flumequine was the more effective with a mean cumulative mortality of 5% compared to oxytetracycline with 54%. The mean cumulative mortality in the unmedicated control groups was 84%. Bacterial examination of kidneys from dead fish confirmed the presence of atypical A. salmonicida as the probable cause of death. Minimum inhibitory concentration (MIC) values for flumequine and oxytetracycline against the isolated A. salmonicida were determined to 0.13 μg ml-1, and 2.0 μg ml-1, respectively. |
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