| one publication added to basket [349823] | Sustainable sunscreens: A challenge between performance, animal testing ban, and human and environmental safety
Pawlowski, S.; Petersen-Thiery, M. (2020). Sustainable sunscreens: A challenge between performance, animal testing ban, and human and environmental safety, in: Tovar-Sanchez, A. et al. Sunscreens in coastal ecosystems: Occurrence, behavior, effect and risk. The Handbook of Environmental Chemistry, 94: pp. 185-207. https://dx.doi.org/10.1007/698_2019_444 In: Tovar-Sanchez, A.; Sánchez-Quiles, D.; Blasco, J. (Ed.) (2020). Sunscreens in coastal ecosystems: Occurrence, behavior, effect and risk. The Handbook of Environmental Chemistry, 94. Springer Nature Switzerland AG: Cham. ISBN 978-3-030-56076-8; e-ISBN 978-3-030-56077-5. XI, 207 pp. https://dx.doi.org/10.1007/978-3-030-56077-5, more In: The Handbook of Environmental Chemistry. Springer: Heidelberg. ISSN 1867-979X; e-ISSN 1616-864X, more |  |
| Author keywords | Environmental safety, Sunscreen, Sustainability, UV filter |
| Authors | | Top | - Pawlowski, S.
- Petersen-Thiery, M.
| | |
| Abstract | The light and warmth of the sun are among the key parameters for the development of many higher life forms on Earth. As light intensity changes within seasons, organisms including mankind have evolved measures to regulate especially UV light intensity to the skin by additional pigmentation, hair, or even feathers. Nowadays, due to increased UV light intensity, change of human movement pattern, and leisure activities, additional sun protection is required. Besides clothes, sunscreen formulations are used to protect human skin from both UV A and UV B radiation. In modern sunscreens, the majority of UV filters are based on organic substances. Aromatic ring structures, high octanol, and low water solubility as well as appropriate chemical stability are needed to meet the criteria of high UV absorbance, sufficient oil solubility, and photostability during the application phase of the sunscreen product. Although naturally occurring substances may provide similar UV absorbance, the lack of chemical stability typically prevents them from being used in such cosmetic products. The high log Pow (typically in the range of 3–6) implies that these substances may accumulate in organisms and thus may cause a threat to top predators. Existing experimentally derived data on various UV filters demonstrate that the bioaccumulation potential remains clearly below critical thresholds (i.e., bioconcentration factor (BCF) is <2,000 and biomagnification factor (BMF) is <1). Due to the direct environmental release of sunscreen products and their UV filters into lakes, rivers, and coastal areas and the overall good environmental stability, chronic aquatic studies are needed to evaluate the substance intrinsic toxicity on various trophic aquatic levels. This is already reflected by the existing European chemical legislation (Registration, Evaluation, Authorisation and Restriction of Chemicals, REACH), which recommends long-term toxicity tests instead of short-term for poorly degradable and poorly water-soluble substances. Furthermore, this regulation also takes into account that additional environmental compartments may be impacted by such type of chemicals and thus requires additional data on soil- and sediment-dwelling organisms at a higher tonnage level.However, besides all given environmental awareness to UV filters in sunscreen products, human and thus consumer safety remains as highest priority. By saying this, in the EU every UV filter used as cosmetic ingredient requires approval by the Scientific Committee on Consumer Safety (SCCS). For the human safety assessment, appropriate information on higher-tier endpoints such as repeated dose toxicity or reproduction toxicity is mandatory in case of significant systemic uptake. However, in contrast to lower-tier tests (such as eye irritation or dermal toxicity), those complex studies cannot be replaced by available in vitro or in silico methods at this time. On the other hand, the existing animal testing ban hinders industry to develop innovative new UV filters since SCCS approval will not be granted due to the lack of relevant data for the safety assessment. |
|
