| one publication added to basket [4121] | Neuroendocrine regulation of growth hormone (GH) release in teleosts: phylogenetic conservations and variations
Rousseau, K.; Le Belle, N.; Vidal, B.; Marchelidon, J.; Boeuf, G.; Dufour, S. (2000). Neuroendocrine regulation of growth hormone (GH) release in teleosts: phylogenetic conservations and variations, in: Norberg, B. et al. (Ed.) Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. pp. 59 In: Norberg, B. et al. (2000). Proceedings of the 6th International Symposium on the Reproductive Physiology of Fish, Bergen, Norway, July 4-9, 1999. International Symposium on the Reproductive Physiology of Fish, 6. Department of Fisheries and Marine Biology, University of Bergen: Bergen. ISBN 82-7461-048-2. 499 pp., more In: International Symposium on the Reproductive Physiology of Fish. Museo Nacional de Ciencias Naturales. , more |
| Authors | | Top | - Rousseau, K.
- Le Belle, N.
- Vidal, B.
| - Marchelidon, J.
- Boeuf, G., more
- Dufour, S.
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| Abstract | Using primary culture of pituitary cells, we studied the regulation of growth hormone (GH) release in two teleosts, the European eel (Anguilla anguilla) and the turbot (Psetta maxima). In both species, we showed that somatotrophs are highly active in vitro, in a serum-free medium and during long-term incubation (at least 12 days). We demonstrated strong inhibitory effects of somatostatin (SRIH) and insulin-like growth factor 1 (IGF1). In the eel, pituitary adenylate-cyclase activating polypeptide (PACAP) and corticoliberin (CRH) were able to stimulate GH release, whereas other neuropeptides such as somatoliberin (GHRH), gonadoliberin (GnRH) and thyreoliberin (TRH) were without effects. In the turbot, no stimulator of GH release has yet been found. Our data, associated with those obtained in different vertebrates, demonstrate a large diversity of factors implicated in the stimulatory control of GH release and a total conservation of the inhibitory control exerted by SRIH and IGF1 |
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