| one publication added to basket [77357] | Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines
de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E. (1995). Short term fasting does not aggravate immunosuppression in harbour seals (Phoca vitulina) with high body burdens of organochlorines. Chemosphere 31(10): 4289-4306 In: Chemosphere. Elsevier: Oxford. ISSN 0045-6535; e-ISSN 1879-1298, more Related to:de Swart, R.L.; Ross, P.S.; Timmerman, H.H.; Hijman, W.C.; De Ruiter, E.; Liem, A.K.D.; Brouwer, A.; van Loveren, H.; Reijnders, P.J.H.; Vos, J.G.; Osterhaus, A.D.M.E. (1995). Short term fasting does not aggravate immunosuppression in harbour seals ( Phoca vitulina) with high body burdens of organochlorines, in: de Swart, R.L. Impaired immunity in seals exposed to bioaccumulated environmental contaminants = Immuunsuppressie in zeehonden blootgesteld aan in de voedselketen geaccumuleerde milieuvervuilende stoffen. pp. 95-110, more |  |
| Keywords | Phoca vitulina Linnaeus, 1758 [WoRMS]
Marine/Coastal |
| Authors | | Top | - de Swart, R.L.
- Ross, P.S.
- Timmerman, H.H.
- Hijman, W.C.
| - De Ruiter, E.
- Liem, A.K.D.
- Brouwer, A.
- van Loveren, H.
| - Reijnders, P.J.H., more
- Vos, J.G.
- Osterhaus, A.D.M.E.
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| Abstract | Two groups of 11 harbour seals (Phoca vitulina) with different body burdens of organochlorines were subjected to an experimental 15-day fasting period, during which they lost an average 16.5% of their body weights. Blood levels of the most persistent organochlorines showed an approximate twofold increase, while levels of aryl hydrocarbon receptor-binding organochlorines remained largely unaffected. Few differences in immunological parameters were observed between the two dietary groups. Numbers of circulating lymphocytes dropped to about 65% of the initial values and NK cell activity showed a slight increase in both groups. Mitogen- and antigen-induced lymphoproliferative responses of the Baltic group of seals remained within normal ranges. These results suggest that relatively short-term fasting periods do not present an additional immunotoxicological risk to seals with high body burdens of organochlorines. |
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