Extensive human/siphonophore genetic sequence overlap: A brief communication
In: Journal of Decolonized Ecology & Evolution. Ashley Gjovik/Center for Open Science: Washington, DC. , more
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| Keywords |
Aquatic organisms > Marine organisms > Aquatic animals > Marine invertebrates
Cnidaria [WoRMS]; Porifera [WoRMS]
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| Author keywords |
BLAST analysis, sequence homology, siphonophore, comparative genomics, evolutionary biology, genome conservation, E-value, phylogenetic analysis, colonial organisms, systematic genomics |
| Abstract |
BLAST analysis using a custom database compiled from NIH and ENA sequences revealed extensive sequence conservation between human genome assemblies and diverse marine invertebrate species. Alignments showed 70-82% identity across 1,762-2,198 base pairs with E-values of 0, indicating extremely high statistical significance indicating non-random alignment. Top matches included cnidarians Nanomia septata and Turritopsis nutricula, gastropods Pupa nitidula, Bosellia mimetica, Tylodina fungina, Microhedyle glandulifera, and Aplysia punctata; echinoderm Cucumaria elongata; amoebas Vermamoeba, Euglypha, and Paraflabellula; and carnivorous demosponge Chondrocladia grandis. The statistical impossibility of such extensive conservation across taxa separated by hundreds of millions of years challenges existing phylogenetic models and demands systemic investigation. |
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