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Unusual 2(1H)-Pyrazinones isolated from a culture of a Brazilian marine-derived Streptomyces sp.
Thomasi, S; Granato, C; Romano, H; Dhooghe, L.; do Nascimento, P; Badino, C; da Silva, F; Ferreira, G; Venancio, T (2014). Unusual 2(1H)-Pyrazinones isolated from a culture of a Brazilian marine-derived Streptomyces sp. Nat. Prod. Commun. 9(9): 1275-1278
In: Natural Product Communications. Natural Products Inc.: Westerville. ISSN 1934-578X; e-ISSN 1555-9475, more
Peer reviewed article  
Available in  Authors 
Keywords
    Streptomyces Waksman & Henrici, 1943 [WoRMS]
    Marine/Coastal
Author keywords
    LC-SPE/NMR; Marine; Streptomyces; Secondary metabolite;2(1H)-Pyrazinones
Authors  Top 
  • Thomasi, S
  • Granato, C
  • Romano, H
  • Dhooghe, L., more
  • do Nascimento, P
  • Badino, C
  • da Silva, F
  • Ferreira, G
  • Venancio, T
Abstract
    Four new secondary metabolites, giovaninones A-D (1-4), were isolated from an ethyl acetate extract of a culture of a marine-derived Streptomyces strain designated SS99BA-2. Chemical analysis was completely conducted in a coupled automated LC-SPE system with the use of a cryogenic NMR probehead and FIRMS. The application of this system to identify, purify and elucidate all the structures is described.
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