Germ-free sea bass Dicentrarchus labrax larval model: a valuable tool in the study of host-microbe interactions
Schaeck, M.; De Swaef, E.; Van Den Broeck, W.; Van Nevel, S.; Boon, N.; De Geyter, N.; Morent, R.; Demeestere, K.; Duchateau, L.; Coulombet, C.; Haesebrouck, F.; Decostere, A. (2016). Germ-free sea bass Dicentrarchus labrax larval model: a valuable tool in the study of host-microbe interactions. Dis. Aquat. Org. 117(3): 177-185. dx.doi.org/10.3354/dao02950 In: Diseases of Aquatic Organisms. Inter Research: Oldendorf/Luhe. ISSN 0177-5103; e-ISSN 1616-1580, more |   |
| Keyword | | | Author keywords | Aquaculture; Gnotobiotic; Pathogen; Larvae |
| Authors | | Top | | - Boon, N., more
- De Geyter, N.
- Morent, R.
- Demeestere, K., more
| - Duchateau, L., more
- Coulombet, C.
- Haesebrouck, F., more
- Decostere, A., more
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| Abstract | A thorough understanding of host-microbe interactions is crucial for more efficient disease management in the marine larviculture industry. As demonstrated in terrestrial animal research, gnotobiotic systems (involving animals cultured in germ-free conditions or inoculated with known microorganisms) are excellent tools to extend our understanding of the mechanisms involved in host-microbe interactions and allow the evaluation of new treatments for diseases. In this study, we introduce a germ-free European sea bass Dicentrarchus labrax larval model, independent of the continuous addition of antimicrobial agents. This model has an experimental set-up that allows addition of live feed to the larvae without compromising the germ-free status. This model will facilitate and render aquaculture research more effective in terms of mitigation fish larval diseases. |
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