Toxicity testing of cosmetic ingredients using gametophyte beads of the brown alga Undaria pinnatifida (Laminariales, Phaeophyta)
Lee, H.; Lee, J.; Brown, M.T.; Park, J.; Vieira, C.; Han, T. (2019). Toxicity testing of cosmetic ingredients using gametophyte beads of the brown alga Undaria pinnatifida (Laminariales, Phaeophyta). J. Appl. Phycol. 31(3): 2011-2023. https://dx.doi.org/10.1007/s10811-018-1669-x In: Journal of Applied Phycology. Springer: Dordrecht. ISSN 0921-8971; e-ISSN 1573-5176, more |  |
| Keywords | Phaeophyceae [WoRMS]; Undaria pinnatifida (Harvey) Suringar, 1873 [WoRMS]
Marine/Coastal | | Author keywords | Phaeophyceae; Undaria pinnatifida; Immobilized gametophytes; Alginatebead; Toxicity test; Cosmetic ingredients |
| Authors | | Top | - Lee, H.
- Lee, J.
- Brown, M.T.
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| Abstract | A 6-h toxicity test of cosmetic ingredients (methylparaben, 2-phenoxyethanol, sodium dodecyl sulfate, triethanolamine) was developed, based on the photosynthetic maximum quantum yield (Fv/Fm) of immobilized gametophytes of the brown macroalga Undaria pinnatifida. From calculated EC50 values, the toxicity ranking of the tested ingredients is: SDS (0.0060%) > MP (0.0634%) > 2-PE (0.2418%) > TEA (3.7023%). Compared to the results from conventional endpoints with other ecotoxicity test organisms, measurements of Fv/Fm is a more sensitive indicator of the toxic effects of cosmetic ingredients. The present technique is simple, rapid, practical, accurate, and requires little space to carry out. This novel method will be a useful tool for assessing the toxicity of a wide range of cosmetic ingredients once the respective sensitivities are fully established. |
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